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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Perindoprilat

Perindoprilat

Perindoprilat Structure
  • ₹0
  • Product name: Perindoprilat
  • CAS: 95153-31-4
  • MF: C17H28N2O5
  • MW: 340.41
  • EINECS:
  • MDL Number:MFCD00865777
  • Synonyms:PERINDOPRILAT;PERINDOPRILAT HYDRATE;(2s-(1(r*(r*)),2-alpha,3a-beta,7a-beta))-) ;1h-indole-2-carboxylicacid,octahydro-1-(2-((1-carboxybutyl)amino)-1-oxopropyl ;(2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-Carboxybutyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;(2S,3aS,7aS)-1-[(S)-2-[[(S)-1-Carboxybutyl]amino]-1-oxopropyl]hexahydroindoline-2-carboxylic acid;S-9780;Perindoprilat ,95%
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Properties

Melting point :153-155°C
Boiling point :568.1±45.0 °C(Predicted)
Density :1.222±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :2.27±0.20(Predicted)
color :White to Pale Beige
Stability :Hygroscopic
CAS DataBase Reference :95153-31-4

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension. Perindoprilat specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Elimination of perindoprilat is decreased in the elderly and in patients with heart or renal failure.

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