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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Phenylbutazone

Phenylbutazone

Phenylbutazone Structure
  • ₹1602 - ₹38645.25
  • Product name: Phenylbutazone
  • CAS: 50-33-9
  • MF: C19H20N2O2
  • MW: 308.37
  • EINECS:200-029-0
  • MDL Number:MFCD00005500
  • Synonyms:Ecobutazone;Elmedal;Equi bute;equibute ;equipalazone ;Eributazone;'Esteve';exrheudonn
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 50MG
  • 100MG
  • 500MG
  • 10gm
  • 25gm
  • 25G
  • 100G
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1686
  • Product descriptionPhenylbutazone
  • Packaging25G
  • Price₹2500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1686
  • Product descriptionPhenylbutazone
  • Packaging500G
  • Price₹7700
  • Updated2022-05-26
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  • ManufacturerSigma-Aldrich(India)
  • Product number79184
  • Product descriptionPhenylbutazone analytical standard
  • Packaging50MG
  • Price₹4708.88
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number80184
  • Product descriptionPhenylbutazone certified reference material, TraceCERT?
  • Packaging100MG
  • Price₹8854.85
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP8386
  • Product descriptionPhenylbutazone
  • Packaging25G
  • Price₹9677.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP8386
  • Product descriptionPhenylbutazone
  • Packaging100G
  • Price₹13271.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2607
  • Product descriptionPhenylbutazone pharmaceutical secondary standard, certified reference material
  • Packaging500MG
  • Price₹14700.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP8386
  • Product descriptionPhenylbutazone
  • Packaging500G
  • Price₹38645.25
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number P 1640
  • Product descriptionPhenylbutazone
  • Packaging10gm
  • Price₹1602
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1640
  • Product descriptionPhenylbutazone
  • Packaging25gm
  • Price₹3996
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1686 Phenylbutazone 25G ₹2500 2022-05-26 Buy
TCI Chemicals (India) P1686 Phenylbutazone 500G ₹7700 2022-05-26 Buy
Sigma-Aldrich(India) 79184 Phenylbutazone analytical standard 50MG ₹4708.88 2022-06-14 Buy
Sigma-Aldrich(India) 80184 Phenylbutazone certified reference material, TraceCERT? 100MG ₹8854.85 2022-06-14 Buy
Sigma-Aldrich(India) P8386 Phenylbutazone 25G ₹9677.55 2022-06-14 Buy
Sigma-Aldrich(India) P8386 Phenylbutazone 100G ₹13271.45 2022-06-14 Buy
Sigma-Aldrich(India) PHR2607 Phenylbutazone pharmaceutical secondary standard, certified reference material 500MG ₹14700.35 2022-06-14 Buy
Sigma-Aldrich(India) P8386 Phenylbutazone 500G ₹38645.25 2022-06-14 Buy
ottokemi P 1640 Phenylbutazone 10gm ₹1602 2022-05-26 Buy
ottokemi P 1640 Phenylbutazone 25gm ₹3996 2022-05-26 Buy

Properties

Melting point :106-108 °C (lit.)
Boiling point :448.76°C (rough estimate)
Density :1.1591 (rough estimate)
refractive index :1.6140 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, sparingly soluble in alcohol. It dissolves in alkaline solutions.
form :Powder
pka :4.5(at 25℃)
color :White to almost white
Water Solubility :<0.1 g/100 mL at 23.5 ºC
Merck :14,7277
BRN :290080
Stability :Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
InChIKey :VYMDGNCVAMGZFE-UHFFFAOYSA-N
LogP :3.160
CAS DataBase Reference :50-33-9(CAS DataBase Reference)
NIST Chemistry Reference :Phenylbutazone(50-33-9)
IARC :3 (Vol. 13, Sup 7) 1987
EPA Substance Registry System :Phenylbutazone (50-33-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phenylbutazone, a nonsteroidal anti-inflammatory drug, is an efficient reducing cofactor for the peroxidase activity of COX. Phenylbutazone-dependent inactivation of COX and prostacyclin synthase is markedly increased in the presence of 100 μM hydrogen peroxide with half-maximal effects at Phenylbutazone concentrations of 100 and 25 μM for COX and prostacyclin synthase, respectively.

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