Melting point :233-234°C
Boiling point :393.35°C (rough estimate)
Density :1.2171 (rough estimate)
refractive index :1.6110 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Prepare the solution immediately before use. Dissolve 0.25 g in a mixture of 1 volume of methanol R and 3 volumes of methylene chloride R and dilute to 10 mL with the same mixture of solvents. The solution is clear (2.2.1) and not more intensely coloured than reference solution BY6 (2.2.2, Method II).
pka :pKa 7(t=20.0) (Uncertain)
form :Solid
color :White to Off-White
Water Solubility :<0.01 g/100 mL at 21 ºC
λmax :276nm(lit.)
Merck :14,7985
BRN :219864
BCS Class :2 (CLogP), 4 (LogP),3
Stability :Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference :58-14-0(CAS DataBase Reference)
IARC :3 (Vol. 13, Sup 7) 1987
NIST Chemistry Reference :Pyrimethamine(58-14-0)
EPA Substance Registry System :Pyrimethamine (58-14-0)

Symbol(GHS):
Signal word:	Warning
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:	P264 Wash hands thoroughly after handling. P264 Wash skin thouroughly after handling. P270 Do not eat, drink or smoke when using this product. P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501 Dispose of contents/container to..…