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ChemicalBook > Product Catalogue >API >Antiparasitic drugs >Antimalarial drugs >Quinine sulfate dihydrate

Quinine sulfate dihydrate

Quinine sulfate dihydrate Structure
  • ₹0
  • Product name: Quinine sulfate dihydrate
  • CAS: 6119-70-6
  • MF: C20H26N2O6S
  • MW: 422.5
  • EINECS:639-128-2
  • MDL Number:MFCD00150790
  • Synonyms:Quinine sulfate fluorescence standard substance;QUININE SULPHATE 2H2O;Quinine sulfate hydrate(2:1:4);CHININI SULFAS;(-)-QUININE SULFATE DIHYDRATE;QUININE SULFATE DIHYDRATE;QUININE SULPHATE DIHYDRATE;Quinine monohydrate hemisulfate salt
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :~225 °C (dec.)(lit.)
alpha :-245 º (c=2, 0.1M HCl)
FEMA :2977 | QUININE SULFATE
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in a mixture of chloroform and absolute alcohol (2:1).
form :Crystalline Powder
color :Light yellow or beige to brown
Odor :odorless
Odor Type :odorless
Water Solubility :0.12 g/100 mL (20 ºC)
Sensitive :Light Sensitive
Merck :14,8061
BRN :6113937
Stability :Stable. Incompatible with strong oxidizing agents, alkalies, ammonia, strong bases, iodine.
InChIKey :AKYHKWQPZHDOBW-QJLYHTAINA-N
SMILES :[C@H]([C@]1([H])C[C@@H]2CC[N@]1C[C@@H]2C=C)(C1=CC=NC2=CC=C(OC)C=C12)O.S(O)(O)(=O)=O |&1:0,1,4,7,9,r|
LogP :3.44
CAS DataBase Reference :6119-70-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

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