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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Food and cosmetics standards >RETRORSINE

RETRORSINE

RETRORSINE Structure
  • ₹23436.13 - ₹86188.65
  • Product name: RETRORSINE
  • CAS: 480-54-6
  • MF: C18H25NO6
  • MW: 351.39
  • EINECS:610-403-9
  • MDL Number:MFCD00870195
  • Synonyms:BETA-LONGILOBINE;12,18-DIHYDROXYSENECIONAN-11,16-DIONE;RETRORSINE;16-dione,12,18-dihydroxy-senecionan-1 ;5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-hydroxymethyl-5-3-ethylidene-4 ;cis-retronecicacidesterofretronecine ;methyl(1,6)dioxacyclododeca(2,3,4-gh)pyrrolizidine-2,7-dione ;trans-15-ethylidene-12beta-hydroxy-12alpha-hydroxymethyl-13beta-methylsenec-1-
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberR0382
  • Product descriptionRetrorsine ≥90% (HPLC)
  • Packaging100MG
  • Price₹23436.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR0382
  • Product descriptionRetrorsine ≥90% (HPLC)
  • Packaging500MG
  • Price₹86188.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) R0382 Retrorsine ≥90% (HPLC) 100MG ₹23436.13 2022-06-14 Buy
Sigma-Aldrich(India) R0382 Retrorsine ≥90% (HPLC) 500MG ₹86188.65 2022-06-14 Buy

Properties

Melting point :208-211 °C (lit.)
alpha :D18 -17.6° (c = 1.99 in ethanol)
Boiling point :485.2°C (rough estimate)
Density :1.32±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.5100 (estimate)
storage temp. :2-8°C
form :Solid
pka :12.00±0.40(Predicted)
color :White to off-white
Merck :13,8253
InChIKey :BCJMNZRQJAVDLD-VMOBWIEOSA-N
CAS DataBase Reference :480-54-6
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Retrorsine (480-54-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Retrorsine, a pyrrolizidine alkaloid, is a mutagenic, antimitotic, and cytotoxic compound. The toxicity of retrorsine relies on its bioactivation by cytochrome P450 enzymes (CYP). The toxicity of retrorsine has been shown to result from one of two compounds that are generated after CYP metabolism of retrorsine.

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