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ChemicalBook > Product Catalogue >API >Antibiotics >Rifamycin drugs >Rifabutin

Rifabutin

Rifabutin Structure
  • ₹7200 - ₹42661.33
  • Product name: Rifabutin
  • CAS: 72559-06-9
  • MF: C46H62N4O11
  • MW: 847
  • EINECS:615-780-3
  • MDL Number:MFCD00866816
  • Synonyms:4-Deoxw3,4-[2-spiro(N-isobutyl-4-pipendyl)]-(1H)-imidazo-(2,5-dihydro)rifamycin S;4-N-ISOBUTYLSPIROPIPERIDYLRIFAMYCIN S;RIFABUTIN;1,4-dihydro-1-deoxy-1’,4-didehydro-5’-(2-methylpropyl)-1-oxo-rifamycinxi ;(9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6,16,18,20-Tetrahydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-hepta-methyl-spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo-[2',3':7,8]-naphth[1,2-d]imidazol-2,4'-piperidin]-5,10,26-(3H,9H)-trione;Ansatipine;Mycobutin;(9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6-16,18,20-Tetrahydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-heptamethylspiro(9,4-(epoxypentadeca(1,11,13)trienimino)-2H-furo(2',3':7,8)naphth(1,2-d)imidazole-2,4'-piperidine)-5,10,26(3H,9H)-trione,16-acetate
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberR0211
  • Product descriptionRifabutin
  • Packaging100MG
  • Price₹7200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0211
  • Product descriptionRifabutin
  • Packaging1G
  • Price₹18600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR3530
  • Product descriptionRifabutin >98% (HPLC), powder
  • Packaging5MG
  • Price₹10597.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2611
  • Product descriptionRifabutin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging100MG
  • Price₹22764.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR3530
  • Product descriptionRifabutin >98% (HPLC), powder
  • Packaging25MG
  • Price₹42661.33
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) R0211 Rifabutin 100MG ₹7200 2022-05-26 Buy
TCI Chemicals (India) R0211 Rifabutin 1G ₹18600 2022-05-26 Buy
Sigma-Aldrich(India) R3530 Rifabutin >98% (HPLC), powder 5MG ₹10597.68 2022-06-14 Buy
Sigma-Aldrich(India) PHR2611 Rifabutin Pharmaceutical Secondary Standard; Certified Reference Material 100MG ₹22764.98 2022-06-14 Buy
Sigma-Aldrich(India) R3530 Rifabutin >98% (HPLC), powder 25MG ₹42661.33 2022-06-14 Buy

Properties

Melting point :169-171°C
Boiling point :969.6±65.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: >5mg/mL
form :powder
pka :3.31±0.70(Predicted)
color :Dark Red to Dark Purple
Water Solubility :0.19g/L(temperature not stated)
BCS Class :2
Stability :Hygroscopic and Light Sensitive
InChIKey :ATEBXHFBFRCZMA-VXTBVIBXSA-N
CAS DataBase Reference :72559-06-9

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Rifamycins are antibiotics that inhibit DNA-dependent RNA polymerases and are usually bactericidal against Gram-positive bacteria but bacteriostatic against Gram-negative bacteria. Rifamycins are also effective against Mycobacterium species, including M. tuberculosis. Rifabutin is a broad-spectrum rifamycin antibiotic that has applications against tuberculosis, H. pylori, M. avium complex, Chlamydia, and other bacteria. It is also useful in co-infections with human immunodeficiency virus, including tuberculosis.

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