SENEGENIN
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- ₹11528.63 - ₹46515.03
- Product name: SENEGENIN
- CAS: 2469-34-3
- MF: C30H45ClO6
- MW: 537.13
- EINECS:
- MDL Number:MFCD00466906
- Synonyms:SENEGENIN;SENEGIN;28-dioicacid,12-(chloromethyl)-2-beta,3-beta-dihydroxy-27-noro-13-ene-2 ;27-Norolean-13-ene-23,28-dioicacid, 12-(chloromethyl)-2,3-dihydroxy-, (2β,3β,4α,12α)-;Tenuigenin;12α-(Chloromethyl)-2β,3β-dihydroxy-27-nor-5α-olean-13-ene-23,28-dioic acid;12α-Chloromethyl-2β,3β-dihydroxy-27-norolean-1-ene-23,28-dioic acid;Tenuifolic acid
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML1001
- Product descriptionSenegenin ≥98% (HPLC)
- Packaging5MG
- Price₹11528.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1001
- Product descriptionSenegenin ≥98% (HPLC)
- Packaging25MG
- Price₹46515.03
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1001 | Senegenin ≥98% (HPLC) | 5MG | ₹11528.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1001 | Senegenin ≥98% (HPLC) | 25MG | ₹46515.03 | 2022-06-14 | Buy |
Properties
Melting point :290-292℃
alpha :D +19° (c = 0.70 in ethanol)
Boiling point :674.1±55.0 °C(Predicted)
Density :1.28
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.27±0.70(Predicted)
form :powder
color :white to beige
alpha :D +19° (c = 0.70 in ethanol)
Boiling point :674.1±55.0 °C(Predicted)
Density :1.28
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.27±0.70(Predicted)
form :powder
color :white to beige
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Tenuigenin is a triterpenoid sapogenin that has been found in P. tenuifolia and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. It inhibits IL-1β and reactive oxygen species (ROS) production from LPS-induced mouse BV2 microglia at a concentration of 4 μM. Tenuigenin (25 mg/kg per day) decreases NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation and prevents dopaminergic neuronal degeneration in the mouse substantia nigra pars compacta in an MPTP-induced model of Parkinson''s disease. Tenuigenin (2 mg/kg) also reduces increases in lung edema and the levels of IL-1β and TNF-α in bronchoalveolar lavage fluid (BALF) in a mouse model of intranasal S. aureus-induced pneumonia.Related product price
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