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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Neuronal Signaling >Adrenergic Receptor Antagonists >Silodosin

Silodosin

Silodosin Structure
  • ₹0
  • Product name: Silodosin
  • CAS: 160970-54-7
  • MF: C25H32F3N3O4
  • MW: 495.53
  • EINECS:814-909-2
  • MDL Number:MFCD00930170
  • Synonyms:Silodoxin;1H-Indole-7-carboxaMide,2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-;KAD 3213;KMD 3213;Urief;Silodosin API;(–)-1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2,3-di-hydro-1H-indole-7-carboxamide;Silodosin
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>104°C (dec.)
alpha :D25 -14.0° (c = 1.01 in methanol)
Boiling point :601.4±55.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Aqueous Base (Slightly, Heated Sonicated), DMSO (Slightly, Sonicated), Methanol
pka :14.85±0.10(Predicted)
form :Solid
color :White to Off-White
InChIKey :PNCPYILNMDWPEY-QGZVFWFLSA-N
SMILES :N1(CCCO)C2=C(C=C(C[C@H](NCCOC3=CC=CC=C3OCC(F)(F)F)C)C=C2C(N)=O)CC1
CAS DataBase Reference :160970-54-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Silodosin is a potent α1A-adrenoceptor antagonist (Ki = 0.036 nM). It shows selectivity for the prostatic adrenoceptor. As a result, it is effective against lower urinary tract symptoms associated with benign prostatic hyperplasia.

More related product prices

160969-03-9 Solifenacin succinate Voriconazole Tamsulosin NCFJJNFEEPMRAQ-XMMPIXPASA-N 1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-1H-indole-7-carboxaMide Paraformaldehyde Silodosin-d4

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Suppliers and manufacturers

Cadila Pharmaceuticals Ltd ALMELO PRIVATE LIMITED Micro Orgo Chem Flax Laboratories Lewens Labs Gonane Pharma KARUNESH REMEDIES Metrochem API Private Limited SVK Laboratories Pvt Ltd Aurobindo Pharma Limited