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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >HDAC inhibitors >Sodium 4-phenylbutyrate

Sodium 4-phenylbutyrate

Sodium 4-phenylbutyrate Structure
  • ₹5800 - ₹16000
  • Product name: Sodium 4-phenylbutyrate
  • CAS: 1716-12-7
  • MF: C10H13NaO2
  • MW: 188.2
  • EINECS:605-612-7
  • MDL Number:MFCD00800247
  • Synonyms:SODIUM 4-PHENYLBUTYRATE;PHENYL N-BUTYRATE SODIUM SALT;4-PHENYLBUTYRATE, NA;4-PHENYLBUTYRIC ACID SODIUM;4-PHENYLBUTYRIC ACID SODIUM SALT;4PBA SODIUM;Nsc657802;SodiuM 4-Phenylbutanoate
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberO0511
  • Product descriptionSodium 4-Phenylbutyrate
  • Packaging1G
  • Price₹5800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberO0511
  • Product descriptionSodium 4-Phenylbutyrate
  • Packaging5G
  • Price₹16000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0309
  • Product descriptionSodium phenylbutyrate ≥98% (HPLC)
  • Packaging100MG
  • Price₹9645.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number567616
  • Product descriptionSodium 4-Phenylbutyrate - CAS 1716-12-7 - Calbiochem A novel anti-neoplastic agent and transcriptional regulator.
  • Packaging100MG
  • Price₹9260
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) O0511 Sodium 4-Phenylbutyrate 1G ₹5800 2022-05-26 Buy
TCI Chemicals (India) O0511 Sodium 4-Phenylbutyrate 5G ₹16000 2022-05-26 Buy
Sigma-Aldrich(India) SML0309 Sodium phenylbutyrate ≥98% (HPLC) 100MG ₹9645.08 2022-06-14 Buy
Sigma-Aldrich(India) 567616 Sodium 4-Phenylbutyrate - CAS 1716-12-7 - Calbiochem A novel anti-neoplastic agent and transcriptional regulator. 100MG ₹9260 2022-06-14 Buy

Properties

Melting point :224-226°C (dec.)
storage temp. :room temp
solubility :H2O: ≥5mg/mL
form :White to slightly yellow solid
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C10H12O2.Na.H/c11-10(12)8-4-7-9-5-2-1-3-6-9;;/h1-3,5-6H,4,7-8H2,(H,11,12);;
InChIKey :OBKXEAXTFZPCHS-UHFFFAOYSA-N
SMILES :C(C1C=CC=CC=1)CCC(=O)O.[NaH]
CAS DataBase Reference :1716-12-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sodium 4-phenylbutyrate is a chemical chaperone that has been shown to rescue the trafficking of misfolded proteins. It also weakly blocks histone deacetylase activity (IC50 = 0.4 mM), which results in cell cycle arrest, differentiation, and/or apoptosis of various tumors. Sodium 4-phenylbutyrate has been tested in clinical trials for the treatment of recurrent malignant gliomas and myelodysplastic syndrome and has long been used for treating urea cycle disorders.

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