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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >Streptozotocin

Streptozotocin

Streptozotocin Structure
  • ₹1791 - ₹158088.3
  • Product name: Streptozotocin
  • CAS: 18883-66-4
  • MF: C8H15N3O7
  • MW: 265.22
  • EINECS:242-646-8
  • MDL Number:MFCD00006607
  • Synonyms:N-(METHYLNITROSOCARBAMOYL)-A-D-GLUCOSAMINE;N-(METHYLNITROSOCARBAMOYL)-ALPHA-D-GLUCOSAMINE;N-(METHYLNITROSOCARBAMOYL)-ALPHA-GLUCOSAMINE;STREPTOZOTOCIN;2-DEOXY-2-(3-METHYL-3-NITROSOUREIDO)-D-GLUCOPYRANOSE;2-DEOXY-2 [([METHYL-NITROSOAMINO]-CARBONYL)-AMINO]-D-GLUCOPYRANOSE;2-DEOXY-2-[[(METHYLNITROSOAMINO)CARBONYL]AMINO]-D-GLUCOSE;U-9889
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Brand

  • Sigma-Aldrich(India)
  • SRL
  • ottokemi

Package

  • 50MG
  • 100MG
  • 250mg
  • 500MG
  • 1gm
  • 1G
  • 5gm
  • 5G
  • 1Gms
  • 5Gms
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0130
  • Product descriptionStreptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder
  • Packaging50MG
  • Price₹4622.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0130
  • Product descriptionStreptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder
  • Packaging100MG
  • Price₹7198.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0130
  • Product descriptionStreptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder
  • Packaging500MG
  • Price₹24994.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0130
  • Product descriptionStreptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder
  • Packaging1G
  • Price₹42737.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0130
  • Product descriptionStreptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder
  • Packaging5G
  • Price₹158088.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number14653
  • Product descriptionStreptozotocin (STZ) extrapure, 98%
  • Packaging100mg
  • Price₹2020
  • Updated2022-05-26
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  • ManufacturerSRL
  • Product number68350
  • Product descriptionStreptozotocin (STZ) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg
  • Packaging100mg
  • Price₹2800
  • Updated2022-05-26
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  • ManufacturerSRL
  • Product number14653
  • Product descriptionStreptozotocin (STZ) extrapure, 98%
  • Packaging250mg
  • Price₹4990
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number14653
  • Product descriptionStreptozotocin (STZ) extrapure, 98%
  • Packaging500mg
  • Price₹9490
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number14653
  • Product descriptionStreptozotocin (STZ) extrapure, 98%
  • Packaging1Gms
  • Price₹17200
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number68350
  • Product descriptionStreptozotocin (STZ) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg
  • Packaging1Gms
  • Price₹19000
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number14653
  • Product descriptionStreptozotocin (STZ) extrapure, 98%
  • Packaging5Gms
  • Price₹75880
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number S 2600
  • Product descriptionStreptozotocin 98%
  • Packaging100mg
  • Price₹1791
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number S 2600
  • Product descriptionStreptozotocin 98%
  • Packaging1gm
  • Price₹14994
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number S 2600
  • Product descriptionStreptozotocin 98%
  • Packaging5gm
  • Price₹62497
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S0130 Streptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder 50MG ₹4622.28 2022-06-14 Buy
Sigma-Aldrich(India) S0130 Streptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder 100MG ₹7198.63 2022-06-14 Buy
Sigma-Aldrich(India) S0130 Streptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder 500MG ₹24994.93 2022-06-14 Buy
Sigma-Aldrich(India) S0130 Streptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder 1G ₹42737.1 2022-06-14 Buy
Sigma-Aldrich(India) S0130 Streptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder 5G ₹158088.3 2022-06-14 Buy
SRL 14653 Streptozotocin (STZ) extrapure, 98% 100mg ₹2020 2022-05-26 Buy
SRL 68350 Streptozotocin (STZ) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg 100mg ₹2800 2022-05-26 Buy
SRL 14653 Streptozotocin (STZ) extrapure, 98% 250mg ₹4990 2022-05-26 Buy
SRL 14653 Streptozotocin (STZ) extrapure, 98% 500mg ₹9490 2022-05-26 Buy
SRL 14653 Streptozotocin (STZ) extrapure, 98% 1Gms ₹17200 2022-05-26 Buy
SRL 68350 Streptozotocin (STZ) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg 1Gms ₹19000 2022-05-26 Buy
SRL 14653 Streptozotocin (STZ) extrapure, 98% 5Gms ₹75880 2022-05-26 Buy
ottokemi S 2600 Streptozotocin 98% 100mg ₹1791 2022-05-26 Buy
ottokemi S 2600 Streptozotocin 98% 1gm ₹14994 2022-05-26 Buy
ottokemi S 2600 Streptozotocin 98% 5gm ₹62497 2022-05-26 Buy

Properties

Melting point :121 °C (dec.) (lit.)
alpha :D25 +39°
Boiling point :408.44°C (rough estimate)
Density :1.4410 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Water (up to 25 mg/ml)
form :powder
pka :pKa 1.3 (Uncertain)
color :white to light yellow
Water Solubility :soluble
Sensitive :Hygroscopic
Merck :13,8912
BRN :2060675
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
InChIKey :ZSJLQEPLLKMAKR-FEQHFJGESA-N
CAS DataBase Reference :18883-66-4
IARC :2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System :Streptozotocin (18883-66-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H228 Flammable solid Flammable solids Category 1
Category 2
Danger
Warning
GHS hazard pictograms P210, P240,P241, P280, P370+P378
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and ATP, and formation of superoxide radicals, leading to the destruction of beta cells. The effectiveness of STZ depends on the level of GLUT2 expression, which in turn may be influenced by age, sex, strain, or species.

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