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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Sulfonamides and synergist >Sulfamerazine sodium

Sulfamerazine sodium

Sulfamerazine sodium Structure
  • ₹9471.88
  • Product name: Sulfamerazine sodium
  • CAS: 127-58-2
  • MF: C11H13N4NaO2S
  • MW: 288.3
  • EINECS:204-851-0
  • MDL Number:MFCD00068332
  • Synonyms:solumedine;SODIUM SULFAMERAZINE;sulfamerazine sodium;SULFAMERAZINE SODIUM SALT;SULFAMERAZINE, SODIUM SALT MONOHYDRATE;monosodium 2-sulfanilamido-4-methylpyrimidine;2-sulfanilamido-4-methylpyrimidine sodium salt;4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE SODIUM SALT
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 250G
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0800
  • Product descriptionSulfamerazine sodium salt
  • Packaging250G
  • Price₹9471.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S0800 Sulfamerazine sodium salt 250G ₹9471.88 2022-06-14 Buy

Properties

RTECS :WP0760000
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
Water Solubility :Soluble in DMSO or water
CAS DataBase Reference :127-58-2(CAS DataBase Reference)
EPA Substance Registry System :Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt (127-58-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sulfamerazine is a sulfonamide antibiotic. It inhibits bacterial carbonic anhydrase by ~20% at a concentration of 500 μM. In vivo, sulfamerazine (500 mg/L) reduces severity of peribronchitis and inhibits cilia-associated respiratory Bacillus colonization in mice. It also prevents death of Toxoplasma-infected mice. Sulfonamide class antibiotics, of which sulfamerazine is a member, are bacteriostatic and inhibit bacterial synthesis of dihydrofolic acid by competing with 4-aminobenzoic acid for binding to dihydropteroate synthase. Formulations containing sulfamerazine have been used for the treatment of pneumonia and typhoid fever.

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