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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Ubiquitin >DUB inhibitors >TCID

TCID

TCID Structure
  • ₹0
  • Product name: TCID
  • CAS: 30675-13-9
  • MF: C9H2Cl4O2
  • MW: 283.92
  • EINECS:
  • MDL Number:MFCD00239209
  • Synonyms:4,5,6,7-TETRACHLOROINDAN-1,3-DIONE;4,5,6,7-TETRACHLOROINDANE-1,3-DIONE;4,5,6,7-TETRACHLORO-1H-INDENE-1,3(2H)-DIONE;4,5,6,7-Tetrachloro-1,3-indanedione;4,5,6,7-Tetrachloroindane-1,3-dione 95+%;4,5,6,7-tetrachloro-2,3-dihydro-1H-indene-1,3-dione;TCID;1H-Indene-1,3(2H)-dione, 4,5,6,7-tetrachloro-
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :218-220
Boiling point :448.1±45.0 °C(Predicted)
Density :1.782±0.06 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 25 mg/ml),
form :Orange solid
pka :8.62±0.20(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) is a deubiquitinating enzyme and thiol-dependent hydrolase. TCID is a tetrachloro indandione that acts as a potent inhibitor of UCH-L3 and demonstrates 125-fold selectivity over UCH-L1 (IC50s = 0.6 and 75 μM, respectively).

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