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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Telmisartan

Telmisartan

Telmisartan Structure
  • ₹7600 - ₹73945.58
  • Product name: Telmisartan
  • CAS: 144701-48-4
  • MF: C33H30N4O2
  • MW: 514.62
  • EINECS:620-494-7
  • MDL Number:MFCD00918125
  • Synonyms:2-[4-[[4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl]methyl]phenyl]benzoic acid;2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propyl-benzimidazol-1-yl]methyl]phenyl]benzoic acid;2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid;4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid;Telmisartan Synonyms 4'[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid;4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-;4'-[{1,4'-Dimethyl-2'-Propyl[2,6'-Bi-1H-Benzimiaszol]-1'yl}-Methyl}-1,1'-Biphenyl-2-Caroxylic Acid Dimethyl Ethyl Ester;4'-[{1,4'-Dimethyl-2'-Propyl[2,6'-Bi-1H-Benzimiaszol]-1'yl}-Methyl}-1,1'-Biphenyl-2-Caroxylic Acid
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 500MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberT2861
  • Product descriptionTelmisartan
  • Packaging1G
  • Price₹7600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2861
  • Product descriptionTelmisartan
  • Packaging5G
  • Price₹19600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT8949
  • Product descriptionTelmisartan ≥98% (HPLC), solid
  • Packaging10MG
  • Price₹18759.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1855
  • Product descriptionTelmisartan Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹18954.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT8949
  • Product descriptionTelmisartan ≥98% (HPLC), solid
  • Packaging50MG
  • Price₹73945.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T2861 Telmisartan 1G ₹7600 2022-05-26 Buy
TCI Chemicals (India) T2861 Telmisartan 5G ₹19600 2022-05-26 Buy
Sigma-Aldrich(India) T8949 Telmisartan ≥98% (HPLC), solid 10MG ₹18759.73 2022-06-14 Buy
Sigma-Aldrich(India) PHR1855 Telmisartan Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹18954.58 2022-06-14 Buy
Sigma-Aldrich(India) T8949 Telmisartan ≥98% (HPLC), solid 50MG ₹73945.58 2022-06-14 Buy

Properties

Melting point :261-263°C
Boiling point :771.9±70.0 °C(Predicted)
Density :1.16
RTECS :DV2037500
storage temp. :2-8°C
solubility :DMSO: >5 mg/mL at 60 °C
pka :3.86±0.36(Predicted)
form :solid
color :white
Water Solubility :insoluble
Merck :14,9129
BCS Class :2
Stability :Hygroscopic
InChIKey :RMMXLENWKUUMAY-UHFFFAOYSA-N
SMILES :C1(C2=CC=C(CN3C(CCC)=NC4=C(C)C=C(C5N(C)C6=CC=CC=C6N=5)C=C43)C=C2)=CC=CC=C1C(O)=O
CAS DataBase Reference :144701-48-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Angiotensin II is a peptide hormone which regulates blood pressure and fluid balance, contributing to hypertension, atherosclerosis, left ventricular hypertrophy, myocardial infarction, and heart failure. Telmisartan is a nonpeptide angiotensin II receptor antagonist which selectively and insurmountably inhibits the angiotensin II AT1 receptor subtype (Ki = 3.7 nM). It also acts as a partial agonist of PPARγ, activating the receptor to 25-30% of that produced by the full agonist rosiglitazone (EC50 = 4.5 μM). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk, and glomerulosclerosis.

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Suppliers and manufacturers

GLR Innovations Jigs Chemical ltd Cadila Pharmaceuticals Ltd HEMA PHARMACEUTICALS PVT LTD SURYA LIFE SCIENCES LIMITED SGMR PHARMACEUTICALS PVT LTD ANWITA APIS J S LABS SEUTIC Prajna generics pvt ltd