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ChemicalBook > Product Catalogue >API >Respiratory Drugs >Asthma drugs >Tiotropium bromide

Tiotropium bromide

Tiotropium bromide Structure
  • ₹7400 - ₹12600
  • Product name: Tiotropium bromide
  • CAS: 136310-93-5
  • MF: C19H22BrNO4S2
  • MW: 472.42
  • EINECS:680-665-7
  • MDL Number:MFCD00867027
  • Synonyms:Anhydrous Tiotropium Bromide;3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide (1:1), (1α,2β,4β,5α,7β)-;(1α,2β,4β,5α,7β-7-[(Hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0^<2,4>^]nonane bromide;Ba-679;Ba-679 BR;otropiuM broMide;(1R,2S,4R,5S,7R)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-diMethyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-9-iuM broMide;TiotropiuM BroMide(Spiriva, BA 679BR)
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 50MG
  • 200MG
  • ManufacturerTCI Chemicals (India)
  • Product numberT3032
  • Product descriptionTiotropium Bromide
  • Packaging50MG
  • Price₹7400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3032
  • Product descriptionTiotropium Bromide
  • Packaging200MG
  • Price₹12600
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T3032 Tiotropium Bromide 50MG ₹7400 2022-05-26 Buy
TCI Chemicals (India) T3032 Tiotropium Bromide 200MG ₹12600 2022-05-26 Buy

Properties

Melting point :218-2200C
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
λmax :240nm(lit.)
Merck :14,9454
CAS DataBase Reference :136310-93-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Tiotropium is a long-acting muscarinic receptor antagonist used as a bronchodilator in the treatment of chronic obstructive pulmonary disease. It binds equally to human muscarinic M1, M2, and M3 receptors (Kds = 0.04, 0.02, and 0.01 nM, respectively), dissociating slowly from M1 and M3 receptors, which are located on bronchial smooth muscle and submucosal glands, and more rapidly from M2 receptors (t? = 14.6 and 34.7 versus 3.6 hours, respectively).

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