Zinquin Ethyl Ester
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- Product name: Zinquin Ethyl Ester
- CAS: 181530-09-6
- MF: C21H22N2O5S
- MW: 414.47
- EINECS:
- MDL Number:MFCD00797629
- Synonyms:ethyl 2-(2-Methyl-8-(4-MethylphenylsulfonaMido)quinolin-6-yloxy)acetate;ZINQUIN ESTER;Acetic Acid, [[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-, Ethyl Ester;ethyl [(2-methyl-8-p-toluenesulfonylaminoquinolin-6-yloxy)acetate];Acetic acid, 2-[[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-, ethyl ester
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Properties
Melting point :112-114°C
Boiling point :578.0±60.0 °C(Predicted)
Density :1.313±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in ethanol, methanol, dimethyl sulfoxide; slightly soluble in water
pka :pK1 (quinoline nitrogen): <2; pK (sulfonamide proton): 9.32 ±0.02(at 25℃)
form :crystals
color :Colorless
λmax :364 nm
Stability :Temperature Sensitive; Store at -20°C
Biological Applications :Zinc indicator; detecting apoptosis
Boiling point :578.0±60.0 °C(Predicted)
Density :1.313±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in ethanol, methanol, dimethyl sulfoxide; slightly soluble in water
pka :pK1 (quinoline nitrogen): <2; pK (sulfonamide proton): 9.32 ±0.02(at 25℃)
form :crystals
color :Colorless
λmax :364 nm
Stability :Temperature Sensitive; Store at -20°C
Biological Applications :Zinc indicator; detecting apoptosis
Safety Information
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Description
Zinquin ethyl ester is a cell-permeable, quinolone-based fluorescent probe used as a zinc indicator. In live cells, cytosolic esterases cleave the ethyl ester group preventing its efflux across the plasma membrane. This probe is UV-excitable and emits in the blue region of the spectrum (excitation 368 nm, emission 490 nm). Zinquin ethyl ester has been used to monitor intracellular zinc fluxes associated with apoptosis.Related product price
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