Astemizole
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- ₹10857.48 - ₹43354.13
- Product name: Astemizole
- CAS: 68844-77-9
- MF: C28H31FN4O
- MW: 458.57
- EINECS:272-441-9
- MDL Number:MFCD00153919
- Synonyms:1-((4-fluorophenyl)methyl)-n-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-1h-b ;r45312 ;retolen ;ASTEMIZOLE;1-[(4-FLUOROPHENYL)METHYL]-N-[1-[2-(4-METHOXYPHENYL)ETHYL]-4-PIPERIDINYL]-1H-BENZIMIDAZOL-2-AMINE;(1-[4-FLUOROBENZYL]-2-[1-(4-METHOXYPHENETHYL)PIPERIDIN-4-YL] AMINOBENZIMIDAZOLE;Astemisan;R 43512
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberA2861
- Product descriptionAstemizole ≥98% (HPLC)
- Packaging10MG
- Price₹10857.48
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA2861
- Product descriptionAstemizole ≥98% (HPLC)
- Packaging50MG
- Price₹43354.13
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A2861 | Astemizole ≥98% (HPLC) | 10MG | ₹10857.48 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A2861 | Astemizole ≥98% (HPLC) | 50MG | ₹43354.13 | 2022-06-14 | Buy |
Properties
Melting point :172.9°C
Boiling point :627.3±65.0 °C(Predicted)
Density :1.1587 (estimate)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :pKa 4.85(H2O t=25.0 I=0.025) (Uncertain);8.69(H2O t=25.0 I=0.025) (Uncertain)
form :powder
color :Crystals
Water Solubility :It is soluble in DMSO (25 mg/ml ), ethanol (25 mg/ml), chloroform, methanol, and water (partly miscible).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Boiling point :627.3±65.0 °C(Predicted)
Density :1.1587 (estimate)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :pKa 4.85(H2O t=25.0 I=0.025) (Uncertain);8.69(H2O t=25.0 I=0.025) (Uncertain)
form :powder
color :Crystals
Water Solubility :It is soluble in DMSO (25 mg/ml ), ethanol (25 mg/ml), chloroform, methanol, and water (partly miscible).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
Symbol(GHS): |
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Description
Astemizole is a non-sedating antihistamine that antagonizes the histamine H1 receptor with a Ki value of 4.4 nM. It is considerably less potent at muscarinic acetylcholine receptors (Ki = 2.4 μM). Astemizole is also a potent blocker of ether-a-go-go-related gene (ERG) potassium channels (IC50 = ~1 nM) that has been used to study long QT syndrome type 2. Furthermore, because it can target oncogenic ERG1 and ERG potassium channels, astemizole has been explored as a potential antineoplastic agent for decreasing proliferation of various cancer cells.More related product prices
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