BAZEDOXIFENE ACETATE
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- ₹12860.1 - ₹52360.53
- Product name: BAZEDOXIFENE ACETATE
- CAS: 198481-33-3
- MF: C32H38N2O5
- MW: 530.67
- EINECS:638-804-4
- MDL Number:MFCD09260074
- Synonyms:BAZEDOXIFENE ACETATE;1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol monoacetate (salt);1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-, monoacetate (salt);Bazedoxifene acetate [usan];Unii-J70472ud3d;Viviant;Way-140424;1-((4-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol monoacetate
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0018
- Product descriptionBazedoxifene acetate ≥98% (HPLC)
- Packaging5MG
- Price₹12860.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0018
- Product descriptionBazedoxifene acetate ≥98% (HPLC)
- Packaging25MG
- Price₹52360.53
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PZ0018 | Bazedoxifene acetate ≥98% (HPLC) | 5MG | ₹12860.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PZ0018 | Bazedoxifene acetate ≥98% (HPLC) | 25MG | ₹52360.53 | 2022-06-14 | Buy |
Properties
Melting point :174-178°
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
color :white to beige
InChIKey :DGEPGJZKMFNSDD-UHFFFAOYSA-N
SMILES :C(=O)(O)C.C(C1C=CC(OCCN2CCCCCC2)=CC=1)N1C2C=CC(O)=CC=2C(C)=C1C1C=CC(O)=CC=1
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
color :white to beige
InChIKey :DGEPGJZKMFNSDD-UHFFFAOYSA-N
SMILES :C(=O)(O)C.C(C1C=CC(OCCN2CCCCCC2)=CC=1)N1C2C=CC(O)=CC=2C(C)=C1C1C=CC(O)=CC=1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Bazedoxifene acetate is a third generation selective estrogen receptor modulator (SERM). It is an indole-based ER ligand that binds to both ERα (IC50 = 26 nM) and ERβ (IC50 = 99 nM). Bazedoxifene actetate antagonizes 17β-estradiol-dependent MCF-7 and T47D breast cancer cell proliferation in vitro as well as hormone-independent growth of MCF-7:5C cells that are resistant to long-term estrogen deprivation (80% reduction with 10 nM). It has been shown to arrest cell cycling by downregulating cyclin D1 and ERα.More related product prices
4-[2-(1-AZEPANYL)ETHOXY]BENZYL CHLORIDE HCL BenzeneMethanol, 4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]- (hydrochloride) 3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE 1-[4-(2-AZEPAN-1-YL-ETHOXY)-BENZYL]-5-BENZYLOXY-2-(4-BENZYLOXY-PHENYL)-3-METHYL-1H-INDOLE Tolvaptan Bazedoxifene 4’-β-D-Glucuronide Hyaluronic acid Sodium tripolyphosphate Sodium metaphosphate 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)(ethoxy-d4)]phenyl]Methyl]-2-(4-hydroxyphenyl)-3-Methyl-Related product price
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₹513-52540.01