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BETA-CYANO-L-ALANINE

BETA-CYANO-L-ALANINE Structure
  • ₹41286.55
  • Product name: BETA-CYANO-L-ALANINE
  • CAS: 6232-19-5
  • MF: C4H6N2O2
  • MW: 114.1
  • EINECS:
  • MDL Number:MFCD00021722
  • Synonyms:H-ALA(3-CN)-OH;H-ALA(BETA-CN)-OH;H-BETA-CYANO-ALA-OH;H-BETA-CYANO-L-ALA-OH;BETA-CYANO-ALANINE;BETA-CYANO-L-ALANINE;B-cyano-L-alanine;H-b-Cyano-Ala-OH
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Brand

  • Sigma-Aldrich(India)

Package

  • 250MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC9650
  • Product descriptionβ-Cyano-L-alanine ≥95%
  • Packaging250MG
  • Price₹41286.55
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C9650 β-Cyano-L-alanine ≥95% 250MG ₹41286.55 2022-06-14 Buy

Properties

Melting point :217 °C
storage temp. :-20°C
solubility :PBS (pH 7.2): 10 mg/ml
form :A crystalline solid
color :White to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

β-cyano-L-Alanine (BCA) is a reversible inhibitor of the H2S-synthesizing enzyme CTH (CSE). BCA blocks H2S synthesis activity in rat liver preparations with an IC50 value of 6.5 μM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H2S synthesis. BCA at 50 mg/kg blocked both L-cysteine- and LPS-induced hyperalgesia in rats. Hydrogen sulfide (H2S) is a naturally-occurring gasotransmitter with vasodilator and inflammatory modulating activity. H2S is synthesized naturally in a range of mammalian tissues principally by the activity of two enzymes, CTH (cystathionine γ lyase CSE) and cystathionineβ synthetase (CBS).

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