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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antifungal Drugs >Bifonazole

Bifonazole

Bifonazole Structure
  • ₹3200 - ₹20978.85
  • Product name: Bifonazole
  • CAS: 60628-96-8
  • MF: C22H18N2
  • MW: 310.4
  • EINECS:262-336-6
  • MDL Number:MFCD00865567
  • Synonyms:Bifonazole for system suitability;Bifonazole Impurity;Biphenylylbenzylazole ;trifonazole ;1-[P,ALPHA-DIPHENYLBENZYL]IMIDAZOLE;1[4,ALPHA-DIPHENYLBENZYL]-IMIDAZOLE;BIFONAZOLE;1-(p,α-diphenylbenzyl)imidazole
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberB4173
  • Product descriptionBifonazole min. 98.0 %
  • Packaging1G
  • Price₹3200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB4173
  • Product descriptionBifonazole min. 98.0 %
  • Packaging5G
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB3563
  • Product descriptionBifonazole ≥98% (HPLC)
  • Packaging10MG
  • Price₹5347.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1296
  • Product descriptionBifonazole Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8107.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB3563
  • Product descriptionBifonazole ≥98% (HPLC)
  • Packaging50MG
  • Price₹20978.85
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B4173 Bifonazole min. 98.0 % 1G ₹3200 2022-05-26 Buy
TCI Chemicals (India) B4173 Bifonazole min. 98.0 % 5G ₹8800 2022-05-26 Buy
Sigma-Aldrich(India) B3563 Bifonazole ≥98% (HPLC) 10MG ₹5347.55 2022-06-14 Buy
Sigma-Aldrich(India) PHR1296 Bifonazole Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8107.93 2022-06-14 Buy
Sigma-Aldrich(India) B3563 Bifonazole ≥98% (HPLC) 50MG ₹20978.85 2022-06-14 Buy

Properties

Melting point :142℃
Boiling point :440.55°C (rough estimate)
Density :1.1150 (rough estimate)
refractive index :1.7620 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO
form :powder
pka :6.55±0.22(Predicted)
color :white to off-white
Merck :14,1213
LogP :4.770
CAS DataBase Reference :60628-96-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Bifonazole is a topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes, molds, yeasts, dimorphic fungi, and some Gram-positive bacteria. It is effective in the treatment of experimental dermatophytic and Candida in animals. Bifonazole is also a potent inhibitor of cytochrome P450 aromatase (Ki = 68 nM, IC50 = 270 nM), which catalyzes the biosynthesis of estrogens from androgens. When applied topically in animals, it demonstrates prolonged retention time in skin with minimal percutaneous absorption, thus minimizing its effect on aromatase.

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