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ChemicalBook > Product Catalogue >API >Digestive system drugs >Laxatives and Antidiarrheal Medicines >Bisacodyl

Bisacodyl

Bisacodyl Structure
  • ₹6400 - ₹20100
  • Product name: Bisacodyl
  • CAS: 603-50-9
  • MF: C22H19NO4
  • MW: 361.39
  • EINECS:210-044-4
  • MDL Number:MFCD00038039
  • Synonyms:2-(4,4’-diacetoxydiphenylmethyl)pyridine ;2-(4,4'-Diacetoxydiphenylmethyl)pyridine;4,4'-(2-Pyridylmethylene)diphenol diacetate;4,4'-(2-Pyridylmethylene)diphenol diacetate (ester);4,4’-(2-pyridinylmethylene)bis-phenodiacetate(ester) ;4,4’-(2-pyridylmethylene)di-phenodiacetate(ester) ;4,4’-(2-pyridylmethylene)-diphenolacetate ;4,4’-(2-Pyridylmethylene)-diphenolace-tate
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 5G
  • 10G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberB5066
  • Product descriptionBisacodyl
  • Packaging5G
  • Price₹6400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB5066
  • Product descriptionBisacodyl
  • Packaging25G
  • Price₹20100
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB1390
  • Product descriptionBisacodyl analytical standard, for drug analysis
  • Packaging10G
  • Price₹12221.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2794
  • Product descriptionBisacodyl certified reference material, pharmaceutical secondary standard
  • Packaging250MG
  • Price₹14473.03
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B5066 Bisacodyl 5G ₹6400 2022-05-26 Buy
TCI Chemicals (India) B5066 Bisacodyl 25G ₹20100 2022-05-26 Buy
Sigma-Aldrich(India) B1390 Bisacodyl analytical standard, for drug analysis 10G ₹12221.43 2022-06-14 Buy
Sigma-Aldrich(India) PHR2794 Bisacodyl certified reference material, pharmaceutical secondary standard 250MG ₹14473.03 2022-06-14 Buy

Properties

Melting point :138°C
Boiling point :493.21°C (rough estimate)
Density :1.2545 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute mineral acids.
pka :4.69±0.10(Predicted)
form :Solid
color :White to Off-White
Water Solubility :Soluble in alcohol (slightly), ether (slightly), chloroform, and acetone. Insoluble in water.
λmax :220nm(MeOH)(lit.)
Merck :14,1242
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :KHOITXIGCFIULA-UHFFFAOYSA-N
LogP :3.453 (est)
CAS DataBase Reference :603-50-9(CAS DataBase Reference)
NIST Chemistry Reference :Bisacodyl(603-50-9)
EPA Substance Registry System :Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) (603-50-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Bisacodyl is used in the inhibition of (Na+K)ATPase, the increase of mucosal PGE2, and the activation of adenyl cyclase in rat intestine studies. It is used as a laxative drug. It is typically prescribed for relief of constipation.

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