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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >Histone Methyltransferase Inhibitors >BRD4770

BRD4770

BRD4770 Structure
  • ₹12394.63 - ₹50076.45
  • Product name: BRD4770
  • CAS: 1374601-40-7
  • MF: C25H23N3O3
  • MW: 413.47
  • EINECS:802-776-3
  • MDL Number:MFCD23143627
  • Synonyms:BRD4770;methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate;methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate BRD4770;2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester;CS-1814;Methyl-2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylate;BRD-4770; BRD 4770;Methyl 2-benzamido-1-(3-phenylpropyl)benzimidazole-5-carboxylate
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0567
  • Product descriptionBRD4770 ≥98% (HPLC)
  • Packaging25MG
  • Price₹50076.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0567
  • Product descriptionBRD4770 ≥98% (HPLC)
  • Packaging5MG
  • Price₹12394.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0567 BRD4770 ≥98% (HPLC) 25MG ₹50076.45 2022-06-14 Buy
Sigma-Aldrich(India) SML0567 BRD4770 ≥98% (HPLC) 5MG ₹12394.63 2022-06-14 Buy

Properties

Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :12.12±0.43(Predicted)
form :powder
color :white to beige
CAS DataBase Reference :1374601-40-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

BRD4770 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, decreasing di- and trimethylation on lysine 9 of histone 3 (EC50 = 5 μM). Through its effects on EHMT2, BRD4770 induces senescence in the pancreatic cancer cell line PANC-1 without initiating apoptosis. It also blocks both anchorage-dependent and –independent proliferation of PANC-1 cells.