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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Fatty alcohols >C16 CERAMIDE

C16 CERAMIDE

C16 CERAMIDE Structure
  • ₹10954.9 - ₹43397.43
  • Product name: C16 CERAMIDE
  • CAS: 24696-26-2
  • MF: C34H67NO3
  • MW: 537.9
  • EINECS:
  • MDL Number:MFCD00056205
  • Synonyms:D-ERYTHRO-SPHINGOSINE, N-PALMITOYL;CERAMIDE-C16;C16 CERAMIDE;C16-D-ERYTHRO-CERAMIDE;C16 ceramide, N-Hexadecanoyl-D-sphingosine, N-Palmitoyl-D-erythro-sphingosine, Palmitoyl ceramide;N-Palmitoyl-D-sphingosine semisynthetic from bovine brain D-sphingosine;N-PALMITOYL-D-ERYTHRO-SPHINGOSINE, SYNTHETICAL, 98% (99+% E.E.);N-Palmitoyl-D-erythro-sphingosineCeramide C16
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • 250MG
  • ManufacturerSigma-Aldrich(India)
  • Product number43799
  • Product descriptionN-Palmitoyl-D-sphingosine ≥98.0% (TLC)
  • Packaging50MG
  • Price₹10954.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number43799
  • Product descriptionN-Palmitoyl-D-sphingosine ≥98.0% (TLC)
  • Packaging250MG
  • Price₹43397.43
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 43799 N-Palmitoyl-D-sphingosine ≥98.0% (TLC) 50MG ₹10954.9 2022-06-14 Buy
Sigma-Aldrich(India) 43799 N-Palmitoyl-D-sphingosine ≥98.0% (TLC) 250MG ₹43397.43 2022-06-14 Buy

Properties

Melting point :94-95 °C
Boiling point :614.41°C (rough estimate)
Density :0.9596 (rough estimate)
refractive index :1.6630 (estimate)
storage temp. :−20°C
solubility :Soluble in DMF at 0.15mg/ml
pka :13.54±0.20(Predicted)
form :Crystalline Powder
color :White
CAS DataBase Reference :24696-26-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires coordinate action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence. C-16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts a lipid second messenger to regulate apoptosis and stress signaling. Accumulation of C-16 ceramide through PPMP (30 μM) or MAPP (50 μM) treatment or from addition of 100 μM synthetic C-16 ceramide induces apoptosis in neutrophil cultures via caspase-3 activation.

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