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ChemicalBook > Product Catalogue >API >Antibiotics >Cephalosporins Drugs >Cefazolin

Cefazolin

Cefazolin Structure
  • ₹18759.73
  • Product name: Cefazolin
  • CAS: 25953-19-9
  • MF: C14H14N8O4S3
  • MW: 454.51
  • EINECS:247-362-8
  • MDL Number:MFCD00243010
  • Synonyms:CEFAZOLIN;(6r-trans)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[(1h-tetr ;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,3-(((5-methyl-1,3,4-thia ;7-(1-(1h-)-tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]d ;azol-1-yl)acetyl]-amino]-5-thia-1-azabicylo ;cefamezin ;CefazoilnV ;cephamezine
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1291
  • Product descriptionCefazolin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹18759.73
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1291 Cefazolin Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹18759.73 2022-06-14 Buy

Properties

Melting point :198-200 C
Density :2.01±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Very Slightly, Heated)
pka :pKa 2.15 (Uncertain)
form :Solid
color :White to Off-White
Stability :Hygroscopic
CAS DataBase Reference :25953-19-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Cefazolin has the natural acetyl side chain at C-3 replaced by a thio-linked thiadiazole ring. Although this group is an activating leaving group, the moiety is not subject to the inactivating host hydrolysis reaction that characterizes cephapirin. At C-7, it possesses a tetrazoylmethylene unit. Cefazolin is less irritating on injection than its cohort in this generation of drugs and has a longer half-life than cephapirin. Its dosing should be reduced in the presence of renal impairment. It is comparatively unstable and should be protected from heat and light.

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Suppliers and manufacturers

Medilink Pharmachem CLEARSYNTH LABS LTD. SynZeal Research Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd Triveni chemicals Unitrade Agencies Pharma Affiliates ORCHID PHARMA LTD
Henan Tianfu Chemical Co.,Ltd.
Xiamen AmoyChem Co., Ltd