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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >Cinobufagin

Cinobufagin

Cinobufagin Structure
  • ₹6800 - ₹22500
  • Product name: Cinobufagin
  • CAS: 470-37-1
  • MF: C26H34O6
  • MW: 442.55
  • EINECS:636-927-8
  • MDL Number:MFCD00056825
  • Synonyms:RARECHEM BK HC T302;5b,20(22)-Bufadienolide-3b,16b-diol-14,15b-epoxy 16-acetate;CINOBUFAGIN95%,99%;CINOBUFAGIN(P);TRANS-3-PHENYLPROPENOIC ACID;TRANS-3-BENZENEPROPENOIC ACID;TRANS-CINNAMYLIC ACID;Cinobufagin std.
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 25MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC3460
  • Product descriptionCinobufagine
  • Packaging25MG
  • Price₹6800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3460
  • Product descriptionCinobufagine
  • Packaging100MG
  • Price₹22500
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3460 Cinobufagine 25MG ₹6800 2022-05-26 Buy
TCI Chemicals (India) C3460 Cinobufagine 100MG ₹22500 2022-05-26 Buy

Properties

Melting point :133 °C(lit.)
Boiling point :300 °C(lit.)
Density :1.261 g/cm3
Flash point :>230 °F
storage temp. :2-8°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
form :powder to crystal
pka :15.10±0.70(Predicted)
color :White to Light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P350 IF ON SKIN: Gently wash with plenty of soap and water.
P310 Immediately call a POISON CENTER or doctor/physician.

Description

Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans, having similar effects to digitalis and used in traditional Chinese medicine. It has potential antineoplastic activity and now is widely used in clinical practice, especially in anti-liver cancer. It has benn found to suppress cancer cell proliferation and cause apoptosis in cancer cells via a sequence of apoptotic modulators, including mitochondrial Bax and cytosolic chromosome c, and caspases 3, 8, and 9.

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