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Clemizole hydrochloride

Clemizole hydrochloride Structure
  • ₹8400 - ₹40994.28
  • Product name: Clemizole hydrochloride
  • CAS: 1163-36-6
  • MF: C19H21Cl2N3
  • MW: 362.3
  • EINECS:214-605-4
  • MDL Number:MFCD00051435
  • Synonyms:allercur ;allercurehydrochloride ;p48 ;1-P-CHLOROBENZYL-2-[1-PYRROLIDINYL]-METHYLBENZIMIDAZOLE HYDROCHLORIDE;1-[(4-Chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzoimidazole hydrochloride;CLEMIZOLE HCL;CLEMIZOLE HYDROCHLORIDE;LABOTEST-BB LT00453174
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC3468
  • Product descriptionClemizole Hydrochloride
  • Packaging25MG
  • Price₹8400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3468
  • Product descriptionClemizole Hydrochloride
  • Packaging100MG
  • Price₹27800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1447
  • Product descriptionClemizole hydrochloride ≥98% (HPLC)
  • Packaging5MG
  • Price₹10164.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1447
  • Product descriptionClemizole hydrochloride ≥98% (HPLC)
  • Packaging25MG
  • Price₹40994.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3468 Clemizole Hydrochloride 25MG ₹8400 2022-05-26 Buy
TCI Chemicals (India) C3468 Clemizole Hydrochloride 100MG ₹27800 2022-05-26 Buy
Sigma-Aldrich(India) SML1447 Clemizole hydrochloride ≥98% (HPLC) 5MG ₹10164.68 2022-06-14 Buy
Sigma-Aldrich(India) SML1447 Clemizole hydrochloride ≥98% (HPLC) 25MG ₹40994.28 2022-06-14 Buy

Properties

Melting point :239-241°
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
Water Solubility :16.84mg/L at 25℃
Merck :14,2346
InChIKey :DNFMJYXRIMLMBZ-UHFFFAOYSA-N
LogP :1.99
CAS DataBase Reference :1163-36-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Clemizole is an antihistamine that antagonizes the histamine 1 receptor at high nanomolar concentrations. It less potently blocks transient receptor potential canonical channel 5 (TRPC5; IC50 = 1.0-1.3 μM), with at least 6-fold selectivity for TRPC5 over other TRP channels. Clemizole also has hepatitis C antiviral action through inhibition of NS4B function, showing synergy with boceprevir , and it inhibits seizures in a zebrafish model of Dravet Syndrome.

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