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D-AP5

D-AP5 Structure
  • ₹4580 - ₹27880
  • Product name: D-AP5
  • CAS: 79055-68-8
  • MF: C5H12NO5P
  • MW: 197.13
  • EINECS:
  • MDL Number:MFCD00078839
  • Synonyms:D-AP5;D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID;D-2-AMINO-5-PHOSPHONOPENTANOIC ACID;D-(-)-2-AMINO-5-PHOSPHONOVALERIC ACID;D(-)-2-Amino-5-phosphonovaleric acid hydrate;D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID (D-AP5);D(-)-AP-5, D(-)-APV, D-2-Amino-5-phosphonovaleric acid;(R)-2-aMino-5-phosphonopentanoic acid
Price4 Properties Safety Information Description
4 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA8054
  • Product descriptionD(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist
  • Packaging1MG
  • Price₹4580
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA8054
  • Product descriptionD(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist
  • Packaging5MG
  • Price₹15090
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number165304
  • Product descriptionD-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.
  • Packaging5MG
  • Price₹16460
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA8054
  • Product descriptionD(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist
  • Packaging10MG
  • Price₹27880
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A8054 D(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist 1MG ₹4580 2022-06-14 Buy
Sigma-Aldrich(India) A8054 D(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist 5MG ₹15090 2022-06-14 Buy
Sigma-Aldrich(India) 165304 D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. 5MG ₹16460 2022-06-14 Buy
Sigma-Aldrich(India) A8054 D(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist 10MG ₹27880 2022-06-14 Buy

Properties

Melting point :approximate 233℃
Boiling point :482.1±55.0 °C(Predicted)
Density :1.529±0.06 g/cm3(Predicted)
RTECS :RD2513000
storage temp. :Store at RT
solubility :Soluble to 100 mM in sterile
form :White solid
pka :2.46±0.10(Predicted)
color :White
Water Solubility :Soluble in water (100mM)
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 μM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (?)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.

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