Doxazosin mesylate
- ₹4600 - ₹53627.05
- Product name: Doxazosin mesylate
- CAS: 77883-43-3
- MF: C24H29N5O8S
- MW: 547.58
- EINECS:1308068-626-2
- MDL Number:MFCD00216023
- Synonyms:ALFADIL;CARDENALIN;DOXAZOSIN MESYLATE;DOXAZOSIN METHANESULFONATE;UK-33274-27;doxazosinmesylate(patented-nosupply) ;piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dihydro-1,4-benzod ;DOXAZOSIN MEYLATE
5 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 50MG
- 100MG
- 250MG
- 500MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberD4126
- Product descriptionDoxazosin Mesylate
- Packaging100MG
- Price₹4600
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberD4126
- Product descriptionDoxazosin Mesylate
- Packaging1G
- Price₹14500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR3310
- Product descriptionDoxazosin mesylate certified reference material, pharmaceutical secondary standard
- Packaging500MG
- Price₹18586.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD9815
- Product descriptionDoxazosin mesylate ≥97% (HPLC), powder
- Packaging250MG
- Price₹53627.05
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD9815
- Product descriptionDoxazosin mesylate ≥97% (HPLC), powder
- Packaging50MG
- Price₹13433.83
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | D4126 | Doxazosin Mesylate | 100MG | ₹4600 | 2022-05-26 | Buy |
TCI Chemicals (India) | D4126 | Doxazosin Mesylate | 1G | ₹14500 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | PHR3310 | Doxazosin mesylate certified reference material, pharmaceutical secondary standard | 500MG | ₹18586.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D9815 | Doxazosin mesylate ≥97% (HPLC), powder | 250MG | ₹53627.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D9815 | Doxazosin mesylate ≥97% (HPLC), powder | 50MG | ₹13433.83 | 2022-06-14 | Buy |
Properties
Melting point :275-277°C
storage temp. :2-8°C
solubility :Slightly soluble in water, soluble in a mixture of 15 volumes of water and 35 volumes of tetrahydrofuran, slightly soluble in methanol, practically insoluble in acetone. It shows polymorphism (5.9), some forms may be hygroscopic
form :powder
color :white
BCS Class :1
Stability :Protect from light
InChIKey :VJECBOKJABCYMF-UHFFFAOYSA-N
CAS DataBase Reference :77883-43-3(CAS DataBase Reference)
storage temp. :2-8°C
solubility :Slightly soluble in water, soluble in a mixture of 15 volumes of water and 35 volumes of tetrahydrofuran, slightly soluble in methanol, practically insoluble in acetone. It shows polymorphism (5.9), some forms may be hygroscopic
form :powder
color :white
BCS Class :1
Stability :Protect from light
InChIKey :VJECBOKJABCYMF-UHFFFAOYSA-N
CAS DataBase Reference :77883-43-3(CAS DataBase Reference)
Safety Information
Symbol(GHS): | ||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||
Precautionary statements: |
|
Description
Doxazosin mesylate is a quinazoline compound that is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. The chemical name of doxazosin mesylate is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate.The empirical formula for doxazosin mesylate is C23H25N505 • CH4O3S and the molecular weight is 547.6.Doxazosin mesylate is freely soluble in dimethylsulfoxide, soluble in dimethylformamide, slightly soluble in methanol, ethanol, and water (0.8% at 25°C), and very slightly soluble in acetone and methylene chloride. Each doxazosin mesylate tablet, for oral administration, contains 1 mg, 2 mg, 4 mg and 8 mg of doxazosin as the free base.
Doxazosin mesylate is a new generation of quinazolone α1 receptor blocker developed by the Pfizer company (United States), It has a long half-life, exerting its effects of dilating the blood vessels, reducing the vascular resistance and lowering the blood pressure through blocking the a 1 receptor. It selectively blocks the a1 adrenergic receptor of the prostate smooth muscle matrix, capsule and bladder neck, alleviating the symptoms of patients of benign prostatic hyperplasia, while having good curing effect on the dysuria caused by simple prostatic hyperplasia. In 1988, doxazosin, as a drug for the treatment of hypertension, had been listed in Denmark. In 1995, the US FDA had approved it for the treatment of benign prostatic hyperplasia. In 2002 September, Doxazosin controlled release tablets had been listed in China, providing a new option for the domestic treatment of benign prostatic hyperplasia. It has been recommended abroad as first-line clinical drugs of anti-hypertension and treatment of prostate disease.
More related product prices
Pazufloxacin mesilate Trifluoromethanesulfonic acid Imatinib Pefloxacin mesylate Diphenyldimethoxysilane Methanesulfonic acid 2,6-Dimethoxybenzaldehyde 1,1-Dimethoxyethane Dimethoxymethane Glycine Dimethyldimethoxysilane Betaine Benzene Quinazoline 1,4-Benzodioxan Doxazosin mesylateRelated product price
- Pazufloxacin mesilate
₹5300-9200 - Trifluoromethanesulfonic acid
₹2015.05-108359.05 - ALTRENOGEST
₹17644.75-116682.68