DPO-1
- ₹84077.78
- Product name: DPO-1
- CAS: 43077-30-1
- MF: C22H29OP
- MW: 340.44
- EINECS:
- MDL Number:MFCD09038567
- Synonyms:DPO-1;[1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide;(+)-Neomenthyl diphenylphosphine oxide;(1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide;DOP-1 (Diphenyl phosphine oxide-1);Phosphine oxide, [(1S,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl-;inhibit,DPO1,Inhibitor,DPO 1,Potassium Channel,DPO-1,KcsA;{[(1S,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl](phenyl)phosphoroso}benzene
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberD7443
- Product descriptionDPO-1 needles, >97% (NMR)
- Packaging25MG
- Price₹84077.78
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D7443 | DPO-1 needles, >97% (NMR) | 25MG | ₹84077.78 | 2022-06-14 | Buy |
Properties
storage temp. :Store at +4°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :needles
color :white
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :needles
color :white
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
DPO-1 is a blocker of Kv1.5 channel and IKur ultrarapid delayed rectifier potassium current. (IC50 = 0.31 μM for rKV1.5). Displays selectivity for inhibition of IKur over Ito (8-fold), IK1, IKr and IKs (20-fold) in native myocytes and selectivity for rat recombinanant KV1.5 over KV3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.Related product price
- 6372-42-5
₹1860-180455 - DPO-1
₹84077.78 - CYCLOHEXYLDIPHENYLPHOSPHINE OXIDE
₹1800-6048