ELLIPTICINE
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- ₹7209 - ₹9490
- Product name: ELLIPTICINE
- CAS: 519-23-3
- MF: C17H14N2
- MW: 246.31
- EINECS:208-264-0
- MDL Number:MFCD00010524
- Synonyms:ELLIPTICINE;5,11-DIMETHYLPYRIDO[4,3-B]CARBAZOLE;5,11-DIMETHYLPYRIDO[4.3:B]CARBAZOLE;5,11-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;3-b)carbazole,5,11-dimethyl-6h-pyrido( ;icig770 ;ELLIPTICINE, FOR FLUORESCENCE;ELLIPTICINE(RG)
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
- ottokemi
Package
- 10MG
- ManufacturerSigma-Aldrich(India)
- Product number324688
- Product descriptionEllipticine - CAS 519-23-3 - Calbiochem A cell-permeable antitumor alkaloid that acts as an inhibitor of topoisomerase II and acts as an intercalative agent that stimulates topoisomerase II-
- Packaging10MG
- Price₹9490
- Updated2022-06-14
- Buy
- Manufacturerottokemi
- Product number E 0656
- Product descriptionEllipticine, ≥99%
- Packaging10mg
- Price₹7209
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 324688 | Ellipticine - CAS 519-23-3 - Calbiochem A cell-permeable antitumor alkaloid that acts as an inhibitor of topoisomerase II and acts as an intercalative agent that stimulates topoisomerase II- | 10MG | ₹9490 | 2022-06-14 | Buy |
| ottokemi | E 0656 | Ellipticine, ≥99% | 10mg | ₹7209 | 2022-05-26 | Buy |
Properties
Melting point :316-318°C
Boiling point :379.31°C (rough estimate)
Density :1.257±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5794 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble
form :Bright yellow solid
pka :16.59±0.40(Predicted)
color :Light yellow to yellow
Merck :13,3581
LogP :4.800
CAS DataBase Reference :519-23-3(CAS DataBase Reference)
Boiling point :379.31°C (rough estimate)
Density :1.257±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5794 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble
form :Bright yellow solid
pka :16.59±0.40(Predicted)
color :Light yellow to yellow
Merck :13,3581
LogP :4.800
CAS DataBase Reference :519-23-3(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Ellipticine is an alkaloid isolated from Apocyanaceae plants that exhibits antitumor activities by intercalating into DNA and/or inhibiting DNA topoisomerase II. It forms covalent adducts in DNA after being enzymatically activated with cytochrome P450 isoforms (e.g., CYP3A4, CYP1A1, or CYP1A2) or by peroxidases in target tissues. Ellipticine has been shown to inhibit the proliferation of human breast adenocarcinoma MCF-7 cells, leukemia HL-60 and CCRF-CEM cells, neuroblastoma IMR-32, UKF-NB-3, and UKF-NB-4 cells, and U87MG glioblastoma cells with IC50 values ranging from 0.27-4.7 μM.More related product prices
ELLIPTICINERelated product price
- ELLIPTICINE
₹7209-9490
