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ChemicalBook > Product Catalogue >Natural Products >Alkaloids >enniatin B1

enniatin B1

enniatin B1 Structure
  • ₹21130.4
  • Product name: enniatin B1
  • CAS: 19914-20-6
  • MF: C34H59N3O9
  • MW: 653.85
  • EINECS:
  • MDL Number:MFCD14635386
  • Synonyms:enniatin B1;2-(N-Methyl-L-isoleucine)enniatin B;3-Butan-2-yl-4,10,16-trimethyl-6,9,12,15,18-penta(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberE5286
  • Product descriptionEnniatin B1 from Gnomonia errabunda, ≥95% (HPLC)
  • Packaging1MG
  • Price₹21130.4
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) E5286 Enniatin B1 from Gnomonia errabunda, ≥95% (HPLC) 1MG ₹21130.4 2022-06-14 Buy

Properties

Melting point :178.5 °C
Boiling point :833.8±65.0 °C(Predicted)
Density :1.031±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL
form :White to off-white crystalline solid.
pka :-1.45±0.70(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Enniatins are cyclohexadepsipeptides commonly isolated from fungi and are known to have antibiotic properties. Many act as ionophores, forming pores in cellular membranes to allow selective ion transport. Enniatin B1 is one of four major analogs of the enniatin complex . It has been shown to induce apoptosis in several cancer lines (EC50s ≤ 10 μM) and to decrease the activation of the cell proliferation kinase, ERK (p44/p42). Enniatin B1 also inhibits the multi-drug resistance transporter Pdr5p from S. cerevisiae and has been used to examine drug resistance mechanisms.

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