Entinostat
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- ₹41373.15 - ₹122387.45
- Product name: Entinostat
- CAS: 209783-80-2
- MF: C21H20N4O3
- MW: 376.41
- EINECS:
- MDL Number:MFCD08272435
- Synonyms:Carbamic acid, N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-, 3-pyridinylmethyl ester;entinostat;3-pyridinylmethyl [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate, N-(2-Aminophenyl)-4-[N-(pyridine-3ylmethoxycarbonyl)aminomethyl]benzamide;N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester;Entinostat/MS-275;Nsc706995;Entinostat(NSC-706995);(Pyridin-3-yl)Methyl 4-(2-AMinophenylcarbaMoyl)benzylcarbaMate
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberEPS002
- Product descriptionMS-275 A HDAC1 and HDAC3 inhibitor
- Packaging1MG
- Price₹41373.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberEPS002
- Product descriptionMS-275 A HDAC1 and HDAC3 inhibitor
- Packaging5MG
- Price₹122387.45
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | EPS002 | MS-275 A HDAC1 and HDAC3 inhibitor | 1MG | ₹41373.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | EPS002 | MS-275 A HDAC1 and HDAC3 inhibitor | 5MG | ₹122387.45 | 2022-06-14 | Buy |
Properties
Melting point :159-160 ºC
Boiling point :566.7±50.0 °C(Predicted)
Density :1.315
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 38 mg/mL, soluble
form :solid
pka :11.32±0.46(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :INVTYAOGFAGBOE-UHFFFAOYSA-N
Boiling point :566.7±50.0 °C(Predicted)
Density :1.315
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 38 mg/mL, soluble
form :solid
pka :11.32±0.46(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :INVTYAOGFAGBOE-UHFFFAOYSA-N
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM). However, it does not inhibit HDAC8 (IC50 > 100 μM). MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell growth, differentiation, and tumor development in vivo. Recent studies suggest that MS-275 may be particularly useful as an antineoplastic agent when combined with other drugs, like adriamycin, inhibitors of poly (ADP-ribose) polymerase (PARP), or inhibitors of heat shock protein 90 (Hsp90).More related product prices
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