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FERUTININ

FERUTININ Structure
  • ₹13726.1
  • Product name: FERUTININ
  • CAS: 41743-44-6
  • MF: C22H30O4
  • MW: 358.47
  • EINECS:
  • MDL Number:MFCD04037015
  • Synonyms:FERUTININ;TEFESTROL;Ferutinin (high purity);Ferutinol p-hydroxybenzoate;Jaeschkeanadiol p-hydroxybenzoate;Ferutinin >=98% (HPLC);Benzoic acid, 4-hydroxy-, (3R,3aS,4S,8aR)-1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl ester;Ferutinin, ERalpha agonist
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1609
  • Product descriptionFerutinin ≥98% (HPLC)
  • Packaging5MG
  • Price₹13726.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1609 Ferutinin ≥98% (HPLC) 5MG ₹13726.1 2022-06-14 Buy

Properties

Boiling point :489.0±45.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: Soluble
form :White to off-white solid
pka :8.12±0.15(Predicted)
color :White to off-white
LogP :5.720 (est)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) α (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM). It also demonstrates ionophoretic properties, increasing calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes at a concentration range of 1-50 μM. Ferutinin is cytotoxic to MCF-7 breast and TCC bladder cancer cells as well as human foreskin HFF3 fibroblasts (IC50s = 29, 24, and 36 μg/ml in vitro after 72 hours of exposure).

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