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Fmoc-Val-Ala-PAB-OH

Fmoc-Val-Ala-PAB-OH Structure
  • ₹9600
  • Product name: Fmoc-Val-Ala-PAB-OH
  • CAS: 1394238-91-5
  • MF: C30H33N3O5
  • MW: 515.6
  • EINECS:
  • MDL Number:MFCD28557282
  • Synonyms:CS-2746;Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;Fmoc-Val-Ala-PAB-OH;Fmoc-Val-ala-PAB;(9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;1-Butanesulfonicacid,6-hydroxy-;Inhibitor,Antibody-drug conjugates linkers,ADC Linkers,Fmoc Val Ala PAB OH,inhibit,FmocValAlaPABOH
Price1 Properties Safety Information Description
1 prices
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Brand

  • TCI Chemicals (India)

Package

  • 250MG
  • ManufacturerTCI Chemicals (India)
  • Product numberF1278
  • Product descriptionFmoc-Val-Ala-PAB-OH
  • Packaging250MG
  • Price₹9600
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F1278 Fmoc-Val-Ala-PAB-OH 250MG ₹9600 2022-05-26 Buy

Properties

Melting point :218 °C(dec.)
Boiling point :811.1±65.0 °C(Predicted)
Density :1.251±0.06 g/cm3(Predicted)
solubility :DMSO : 33.33 mg/mL (64.64 mM; ultrasonic and warming and heat to 80°C)
pka :10.63±0.46(Predicted)
form :powder to crystal
color :White to Light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Fmoc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

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Suppliers and manufacturers

Henan Aochuang Chemical Co.,Ltd.
Fmoc-Val-Ala-PAB-OH
₹0.00 /1KG
Fmoc-Val-Ala-PAB-OH CAS:1394238-91-5
TCI Chemicals (India) Pvt. Ltd. CLEARSYNTH LABS LTD.
ATK CHEMICAL COMPANY LIMITED
Jinan Carbotang Biotech Co.,Ltd.
Finetech Industry Limited
Zhejiang J&C Biological Technology Co.,Limited
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Nextpeptide Inc
TargetMol Chemicals Inc.