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ChemicalBook > Product Catalogue >Natural Products >Alkaloids >FUMITREMORGIN C

FUMITREMORGIN C

FUMITREMORGIN C Structure
  • ₹21460 - ₹27116.63
  • Product name: FUMITREMORGIN C
  • CAS: 118974-02-0
  • MF: C22H25N3O3
  • MW: 379.45
  • EINECS:
  • MDL Number:MFCD08702652
  • Synonyms:FuMitreMorgin CFuMitreMorg;(5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione;12alpha-Fumitremorgin C;5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione,1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-,(5aS,12S,14aS)-;Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem;Fumitremorgin C, 98%, from Aspergillus fumigatus;12α-Fumitremorgin C;Fumitremorgin C, from Aspergillus fumigatus
Price2 Properties Safety Information Description
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 250μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberF9054
  • Product descriptionFumitremorgin C from Neosartorya fischeri, film
  • Packaging250μG
  • Price₹27116.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number344847
  • Product descriptionFumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug tran
  • Packaging250μG
  • Price₹21460
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) F9054 Fumitremorgin C from Neosartorya fischeri, film 250μG ₹27116.63 2022-06-14 Buy
Sigma-Aldrich(India) 344847 Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug tran 250μG ₹21460 2022-06-14 Buy

Properties

Melting point :259.5-260.5℃
Boiling point :642.9±55.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :acetonitrile: 5 mg/mL, soluble
pka :17.16±0.40(Predicted)
form :solid
color :White to light brown

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).

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