Gimeracil
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- ₹6635.73 - ₹16075.13
- Product name: Gimeracil
- CAS: 103766-25-2
- MF: C5H4ClNO2
- MW: 145.54
- EINECS:1312995-182-4
- MDL Number:MFCD08458352
- Synonyms:GIMERACIL;gimestat;5-Chloro-2,4-dihydroxypyridine;5-Chloro-4-hydroxy-2(1H)-pyridinone;5-Chloro-4-hydroxy-2-pyridone;2(1H)-Pyridinone,5-chloro-4-hydroxy-(9CI);5-chloropyridine-2,4-diol;2(1H)-Pyridinone, 5-chloro-4-hydroxy-
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 1G
- 5G
- ManufacturerTCI Chemicals (India)
- Product numberC2243
- Product descriptionGimeracil
- Packaging1G
- Price₹6800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC2243
- Product descriptionGimeracil
- Packaging5G
- Price₹15000
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2075
- Product descriptionGimeracil ≥98% (HPLC)
- Packaging5MG
- Price₹6635.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2075
- Product descriptionGimeracil ≥98% (HPLC)
- Packaging25MG
- Price₹16075.13
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | C2243 | Gimeracil | 1G | ₹6800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C2243 | Gimeracil | 5G | ₹15000 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML2075 | Gimeracil ≥98% (HPLC) | 5MG | ₹6635.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML2075 | Gimeracil ≥98% (HPLC) | 25MG | ₹16075.13 | 2022-06-14 | Buy |
Properties
Melting point :274 °C
Boiling point :255.1±40.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
pka :4.50±1.00(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :ZPLQIPFOCGIIHV-UHFFFAOYSA-N
CAS DataBase Reference :103766-25-2(CAS DataBase Reference)
Boiling point :255.1±40.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
pka :4.50±1.00(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :ZPLQIPFOCGIIHV-UHFFFAOYSA-N
CAS DataBase Reference :103766-25-2(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine, which is required for DNA synthesis. It has been widely used to treat many gastrointestinal tract adenocarcinomas with mixed clinical efficacy. Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, the rate limiting enzyme for the catabolism of pyrimidines, including 5-fluorouracil. It has been administered concomitantly with 5-fluorouracil in a chemotherapy regimen termed S-1 to block 5-fluorouracil degradation, thus prolonging circulating 5-fluorouracil concentrations. Furthermore, at 1 mM gimeracil has been shown to inhibit homologous recombination in the repair of DNA double strand breaks, which can sensitize cancer cells to radiotherapy.More related product prices
Clopidol 2-Chloro-5-chloromethylpyridine 2,4-Dihydroxypyridine GimeracilRelated product price
- Clopidol
₹11355.43 - 2-Chloro-5-chloromethylpyridine
₹2600-10034.78 - 2,4-Dihydroxypyridine
₹2046-24864
