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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >(+)-Griseofulvin

(+)-Griseofulvin

(+)-Griseofulvin Structure
  • ₹2200 - ₹28989.35
  • Product name: (+)-Griseofulvin
  • CAS: 126-07-8
  • MF: C17H17ClO6
  • MW: 352.77
  • EINECS:204-767-4
  • MDL Number:MFCD00082343
  • Synonyms:7-Chloro-2,4,6-trimethoxy-6-methyl-, (1S-trans)-Spiro(benzofuran-2(3H),1-(2)cyclohexene)-3,4-dione;Griseofulvin, (2S)-trans-7-Chloro-2μ,4,6-trimethoxy-6μ-methylspiro(benzofuran-2[3H],1μ-[2]cyclohexene)-3,4μ-dione;7-Chloro-2',4,6-trimethoxy-6'b-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione;Grisact;(+)-Griseofulvin,97%;GRISEOFULVIN(RG);Griseofulvin (200 mg);Griseofulvin (200 mg)I1D406992ug/mg(ai)
6 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • 25G
  • 50G
  • ManufacturerTCI Chemicals (India)
  • Product numberG0384
  • Product description(+)-Griseofulvin
  • Packaging5G
  • Price₹2200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberG0384
  • Product description(+)-Griseofulvin
  • Packaging25G
  • Price₹5600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG4753
  • Product descriptionGriseofulvin from Penicillium griseofulvum, 97.0-102.0%
  • Packaging5G
  • Price₹4849.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1534
  • Product descriptionGriseofulvin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9103.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG4753
  • Product descriptionGriseofulvin from Penicillium griseofulvum, 97.0-102.0%
  • Packaging25G
  • Price₹19322.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG4753
  • Product descriptionGriseofulvin from Penicillium griseofulvum, 97.0-102.0%
  • Packaging50G
  • Price₹28989.35
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) G0384 (+)-Griseofulvin 5G ₹2200 2022-05-26 Buy
TCI Chemicals (India) G0384 (+)-Griseofulvin 25G ₹5600 2022-05-26 Buy
Sigma-Aldrich(India) G4753 Griseofulvin from Penicillium griseofulvum, 97.0-102.0% 5G ₹4849.6 2022-06-14 Buy
Sigma-Aldrich(India) PHR1534 Griseofulvin Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9103.83 2022-06-14 Buy
Sigma-Aldrich(India) G4753 Griseofulvin from Penicillium griseofulvum, 97.0-102.0% 25G ₹19322.63 2022-06-14 Buy
Sigma-Aldrich(India) G4753 Griseofulvin from Penicillium griseofulvum, 97.0-102.0% 50G ₹28989.35 2022-06-14 Buy

Properties

Melting point :218-220 °C(lit.)
alpha :354 º (c=1, dimethylform)
Boiling point :469.04°C (rough estimate)
Density :1.2579 (rough estimate)
refractive index :1.4429 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in dimethylformamide and in tetrachloroethane, slightly soluble in anhydrous ethanol and in methanol
form :Powder
color :White to yellow-white
Water Solubility :practically insoluble
λmax :321nm(CHCl3)(lit.)
Merck :14,4549
BRN :95226
BCS Class :2 (CLogP), 4 (LogP)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol, or DMF may be stored at -20° for up to 3 months.
InChIKey :DDUHZTYCFQRHIY-RBHXEPJQSA-N
LogP :2.180
CAS DataBase Reference :126-07-8(CAS DataBase Reference)
NIST Chemistry Reference :Griseofulvin(126-07-8)
IARC :2B (Vol. Sup 7, 79) 2001
EPA Substance Registry System :Griseofulvin (126-07-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Griseofulvin is a natural bacterial product used, in certain formulations, as an oral antibiotic for fungal infections of the skin. It alters microtubule dynamics, resulting in metaphase arrest. Antimicrotubule agents, including griseofulvin, have potential applications in cancer therapy, particularly when combined with other chemotherapeutic compounds.

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