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ChemicalBook > Product Catalogue >Natural Products >Flavonoids >HISPIDULIN

HISPIDULIN

HISPIDULIN Structure
  • ₹12827.63 - ₹52198.15
  • Product name: HISPIDULIN
  • CAS: 1447-88-7
  • MF: C16H12O6
  • MW: 300.26
  • EINECS:
  • MDL Number:MFCD00143504
  • Synonyms:SCUTELLAREIN 6-METHYL ETHER;4',5,7-Trihydroxy-6-methoxyflavone;5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;6-Methoxyapigenin;6-Methylscutellarein;Hispidulin(Dinatin);Methoxyapigenin;Dinatin
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0582
  • Product descriptionHispidulin ≥98% (HPLC)
  • Packaging5MG
  • Price₹12827.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0582
  • Product descriptionHispidulin ≥98% (HPLC)
  • Packaging25MG
  • Price₹52198.15
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0582 Hispidulin ≥98% (HPLC) 5MG ₹12827.63 2022-06-14 Buy
Sigma-Aldrich(India) SML0582 Hispidulin ≥98% (HPLC) 25MG ₹52198.15 2022-06-14 Buy

Properties

Melting point :291-292 °C
Boiling point :601.5±55.0 °C(Predicted)
Density :1.512±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :6.51±0.40(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Hispidulin is a natural flavanoid which acts as a potent benzodiazepine (BZD) receptor ligand. In addition, hispidulin competitively binds to the benzodiazepine receptor, thus inhibiting 3H-Flumazenil from binding to the receptor. Furthermore, it has been observed that hispidulin has antioxidant, antithrombotic, antifungal, and antiproliferative properties. Alternate studies indicate that hispidulin can inhibit the PI3K/Akt/mTOR signaling pathway in endothelial cells by targeting VEGF receptor 2. Inhibition of this receptor by hispidulin suppressed cell migration, invasion, and capillary-like structure formation of HU-VE-Cs in vascular endothelial cells. Hispidulin also aactivates AMPK.

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