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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Ibuprofen

Ibuprofen

Ibuprofen Structure
  • ₹3247.5 - ₹23900
  • Product name: Ibuprofen
  • CAS: 15687-27-1
  • MF: C13H18O2
  • MW: 206.28
  • EINECS:239-784-6
  • MDL Number:MFCD00010393
  • Synonyms:IBUPROFEN IMP. J (EP):(2RS)2-(4-ISOBUTYRYLPHENYL)PROPANOIC ACID MM(CRM STANDARD);IBUPROFEN IMP.R (EP): 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE MM(CRM STANDARD);IBUPROFEN WHO STANDARD;IBUPROFEN USP STANDARD;IBUPROFEN IMP. A (EP): 2-(3-ISOBUTYLPHENYL)PROPANOIC ACID MM(CRM STANDARD);IBUPROFEN IMP. B (EP): 2-(4-BUTYLPHENYL)PROPANOIC ACID MM(CRM STANDARD);IBUPROFEN IMP. F (EP): 3-(4-ISOBUTYLPHENYL)PROPIONIC ACID MM(CRM STANDARD);IBUPROFEN IMP. D (EP): 2-(4-METHYLPHENYL)PROPANOIC ACID MM(CRM STANDARD)
12 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 1ML
  • 1G
  • 1gm
  • 5gm
  • 5G
  • 25G
  • 100G
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberI0415
  • Product descriptionIbuprofen min. 98.0 %
  • Packaging25G
  • Price₹5100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0415
  • Product descriptionIbuprofen min. 98.0 %
  • Packaging100G
  • Price₹15600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0415
  • Product descriptionIbuprofen min. 98.0 %
  • Packaging500G
  • Price₹23900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI4883
  • Product descriptionIbuprofen ≥98% (GC)
  • Packaging5G
  • Price₹15479.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI110
  • Product descriptionIbuprofen
  • Packaging5G
  • Price₹12935.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1004
  • Product descriptionIbuprofen Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8356.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number401003
  • Product description(±)-Ibuprofen - CAS 15687-27-1 - Calbiochem A nonsteroidal anti-inflammatory drug (NSAID) that acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC?? = 4.85 μM).
  • Packaging1G
  • Price₹8310
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI4883
  • Product descriptionIbuprofen ≥98% (GC)
  • Packaging1G
  • Price₹5336.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI-009
  • Product descriptionIbuprofen solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹3311.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI110
  • Product descriptionIbuprofen
  • Packaging1G
  • Price₹3247.5
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number I 5871
  • Product descriptionIbuprofen, ≥98% 98%
  • Packaging5gm
  • Price₹14004
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number I 5871
  • Product descriptionIbuprofen, ≥98% 98%
  • Packaging1gm
  • Price₹4806
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0415 Ibuprofen min. 98.0 % 25G ₹5100 2022-05-26 Buy
TCI Chemicals (India) I0415 Ibuprofen min. 98.0 % 100G ₹15600 2022-05-26 Buy
TCI Chemicals (India) I0415 Ibuprofen min. 98.0 % 500G ₹23900 2022-05-26 Buy
Sigma-Aldrich(India) I4883 Ibuprofen ≥98% (GC) 5G ₹15479.75 2022-06-14 Buy
Sigma-Aldrich(India) I110 Ibuprofen 5G ₹12935.88 2022-06-14 Buy
Sigma-Aldrich(India) PHR1004 Ibuprofen Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8356.9 2022-06-14 Buy
Sigma-Aldrich(India) 401003 (±)-Ibuprofen - CAS 15687-27-1 - Calbiochem A nonsteroidal anti-inflammatory drug (NSAID) that acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC?? = 4.85 μM). 1G ₹8310 2022-06-14 Buy
Sigma-Aldrich(India) I4883 Ibuprofen ≥98% (GC) 1G ₹5336.73 2022-06-14 Buy
Sigma-Aldrich(India) I-009 Ibuprofen solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹3311.7 2022-06-14 Buy
Sigma-Aldrich(India) I110 Ibuprofen 1G ₹3247.5 2022-06-14 Buy
ottokemi I 5871 Ibuprofen, ≥98% 98% 5gm ₹14004 2022-05-26 Buy
ottokemi I 5871 Ibuprofen, ≥98% 98% 1gm ₹4806 2022-05-26 Buy

Properties

Melting point :77-78 °C
Boiling point :157 °C (4 mmHg)
alpha :[α]D20 -1~+1°(c=1,C2H5OH)
Density :1.0364 (rough estimate)
refractive index :1.5500 (estimate)
Flash point :9℃
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in acetone, in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides and carbonates.
pka :pKa 4.45± 0.04(H2O,t = 25±0.5,I=0.15(KCl))(Approximate)
form :Crystalline Powder
color :white to off-white
Water Solubility :insoluble
Merck :14,4881
BCS Class :2
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey :HEFNNWSXXWATRW-UHFFFAOYSA-N
LogP :3.970
CAS DataBase Reference :15687-27-1(CAS DataBase Reference)
NIST Chemistry Reference :Ibuprofen(15687-27-1)
EPA Substance Registry System :Benzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl)- (15687-27-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ibuprofen is a nonsteroidal anti-inflammatory analgesic. Its anti-inflammatory, analgesic and antipyretic effect is good, has less adverse reactions. Nowadays, it has already widely used in the world, and is to become one of the most popular over-the-counter medications in the world, and is listed as antipyretic analgesic three pillars products with aspirin, acetaminophen.
Ibuprofen was co-found by Dr Stewart Adams (later became a professor and was awarded a MBE) and his leadership team, scientific research expert CoLinBurrows, chemical expert Dr John Nicholson. The original research purpose was invention of a "super aspirin", to replace drug of aspirin with less serious adverse reactions for the treatment of rheumatoid arthritis. And other drugs, such as Bute, has a greater risk of agranulocytosis occurred; Corticosteroid drugs, larger dosage than ordinary prescription dose brings the adrenal suppression and other adverse reactions, such as high risk of gastrointestinal ulcers, etc. Adams decided to find a drug with good gastrointestinal tolerance, this feature for all classes of non-steroidal anti-inflammatory drugs (nsaids) are particularly important on the current.

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