ILOPROST
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- ₹13726.1 - ₹55077.6
- Product name: ILOPROST
- CAS: 78919-13-8
- MF: C22H32O4
- MW: 360.49
- EINECS:
- MDL Number:MFCD00867145
- Synonyms:(16r,s)-methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandini(sub2) ;1h)-pentalenylidene)- ;pentanoicacid,5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2( ;zk36374 ;6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-16-METHYL-PROSTA-5E,13E-DIEN-18-YN-1-OIC ACID;Endoprost;Ilomedin;(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]pentanoicacid
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML1651
- Product descriptionIloprost ≥98% (HPLC)
- Packaging1MG
- Price₹13726.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1651
- Product descriptionIloprost ≥98% (HPLC)
- Packaging5MG
- Price₹55077.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1651 | Iloprost ≥98% (HPLC) | 1MG | ₹13726.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1651 | Iloprost ≥98% (HPLC) | 5MG | ₹55077.6 | 2022-06-14 | Buy |
Properties
Boiling point :539.2±50.0 °C(Predicted)
Density :1.210±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in methyl acetate
pka :4.77±0.10(Predicted)
form :film
color :colorless
Stability :Light Sensitive
Density :1.210±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in methyl acetate
pka :4.77±0.10(Predicted)
form :film
color :colorless
Stability :Light Sensitive
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the human recombinant IP and EP1 receptors with a Ki of 11 nM. Iloprost constricts the isolated guinea pig ilium and fundus circular smooth muscle (an EP1 receptor preparation) as strongly as prostaglandin E2 (PGE2) itself. Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. It has been evaluated in several human clinical studies as a treatment for idiopathic pulmonary hypertension. In these studies, an aerosolized dose of 30 μg/day was effective, and doses as high as 150 μg/day for up to a year were well tolerated.More related product prices
