Loratadine
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- ₹3600 - ₹64679.38
- Product name: Loratadine
- CAS: 79794-75-5
- MF: C22H23ClN2O2
- MW: 382.88
- EINECS:935-907-9
- MDL Number:MFCD00672869
- Synonyms:LORATADINE;LORATADINE-D5;4-(8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cycloheptene-5-ylidene)piperidine-1-carboxylic acid ethyl ester;4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine-11-ylidene)piperidine-1-carboxylic acid ethyl ester;Loratadine,4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Loratidine;anium wilfordii Maxim;4(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLATE;4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER
5 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
Package
- 10MG
- 50MG
- 100MG
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1376
- Product descriptionLoratadine Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹11160.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL9664
- Product descriptionLoratadine ≥98% (HPLC), powder
- Packaging10MG
- Price₹16183.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL9664
- Product descriptionLoratadine ≥98% (HPLC), powder
- Packaging50MG
- Price₹64679.38
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0223
- Product descriptionLoratadine
- Packaging1G
- Price₹8600
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0223
- Product descriptionLoratadine
- Packaging100MG
- Price₹3600
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR1376 | Loratadine Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹11160.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L9664 | Loratadine ≥98% (HPLC), powder | 10MG | ₹16183.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L9664 | Loratadine ≥98% (HPLC), powder | 50MG | ₹64679.38 | 2022-06-14 | Buy |
TCI Chemicals (India) | L0223 | Loratadine | 1G | ₹8600 | 2022-05-26 | Buy |
TCI Chemicals (India) | L0223 | Loratadine | 100MG | ₹3600 | 2022-05-26 | Buy |
Properties
Melting point :134-136°C
Boiling point :531.3±50.0 °C(Predicted)
Density :1.261±0.06 g/cm3(Predicted)
RTECS :TM6129200
storage temp. :2-8°C
solubility :DMSO: 26 mg/mL, soluble
form :powder
pka :4.27±0.20(Predicted)
color :white
Water Solubility :It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck :14,5578
BCS Class :2
Stability :Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKey :JCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference :79794-75-5(CAS DataBase Reference)
EPA Substance Registry System :1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Boiling point :531.3±50.0 °C(Predicted)
Density :1.261±0.06 g/cm3(Predicted)
RTECS :TM6129200
storage temp. :2-8°C
solubility :DMSO: 26 mg/mL, soluble
form :powder
pka :4.27±0.20(Predicted)
color :white
Water Solubility :It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck :14,5578
BCS Class :2
Stability :Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKey :JCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference :79794-75-5(CAS DataBase Reference)
EPA Substance Registry System :1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Safety Information
Symbol(GHS): |
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Description
Loratadine is a non-sedating antihistamine that acts as a selective inverse agonist of peripheral histamine H1 receptors (Ki = 35 nM). It has been shown to inhibit the release of leukotriene C4 (IC50 = 8 μM) and histamine (IC50 = 11 μM) from rodent mast cells and to inhibit allergic bronchospasm in guinea pigs with an ED50 value of 0.40 mg/kg.More related product prices
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