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LY 303511

LY 303511 Structure
  • ₹15469.99
  • Product name: LY 303511
  • CAS: 154447-38-8
  • MF: C19H18N2O2
  • MW: 306.36
  • EINECS:
  • MDL Number:MFCD03453556
  • Synonyms:LY 303511; LY303511;2-(1-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one;8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one;8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one LY303511;LY303511, >=98%;4H-1-Benzopyran-4-one, 8-phenyl-2-(1-piperazinyl)-;LY-303511(Nv-128);8-phenyl-2-(piperazin-1-yl)-4H-chromen-4-one
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product number440203
  • Product descriptionLY 303511 - CAS 154447-38-8 - Calbiochem A cell-permeable negative control for the PI 3-kinase inhibitor LY 294002.
  • Packaging1MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 440203 LY 303511 - CAS 154447-38-8 - Calbiochem A cell-permeable negative control for the PI 3-kinase inhibitor LY 294002. 1MG ₹15469.99 2022-06-14 Buy

Properties

Boiling point :496.1±45.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
form :Amber solid
pka :9.20±0.10(Predicted)

Safety Information

Symbol(GHS):
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Description

LY 303511 is a cell-permeable chemical that exhibits antineoplastic actions independent of PI 3-kinase inhibition. LY 303511 was first discovered as an inactive analog of LY294002 (Catalog SC-215273) which does not inhibit PI 3-kinase, but recent research has shown LY 303511 to block cell proliferation via mTOR-dependent and independent mechanisms, without inducing apoptosis. LY 303511 has been shown to reduce G2M progression, G2M-specific cyclins and casein kinase 2 activity in A549 cells. It can be used as a negative control for the PI 3-kinase inhibitor LY294002.

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