Mebendazole
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- ₹2800 - ₹22764.98
- Product name: Mebendazole
- CAS: 31431-39-7
- MF: C16H13N3O3
- MW: 295.29
- EINECS:250-635-4
- MDL Number:MFCD00057872
- Synonyms:(5-benzoyl-1h-benzimidazol-2-yl)-carbamicacidmethylester ;(5-benzoyl-1h-benzimidazol-2-yl)-carbamicacimethylester ;5-benzoyl-2-benzimidazolecarbamicacimethylester ;bantenol ;besantin ;lomper ;mbdz ;mebenvet
5 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 250MG
- 300MG
- 5G
- 25G
- ManufacturerTCI Chemicals (India)
- Product numberM2273
- Product descriptionMebendazole
- Packaging5G
- Price₹2800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM2273
- Product descriptionMebendazole
- Packaging25G
- Price₹6800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM2523
- Product descriptionMebendazole analytical standard, ≥98% (HPLC)
- Packaging25G
- Price₹9374.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number46404
- Product descriptionMebendazole VETRANAL?, analytical standard
- Packaging250MG
- Price₹11669.35
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2448
- Product descriptionMebendazole Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging300MG
- Price₹22764.98
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | M2273 | Mebendazole | 5G | ₹2800 | 2022-05-26 | Buy |
TCI Chemicals (India) | M2273 | Mebendazole | 25G | ₹6800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | M2523 | Mebendazole analytical standard, ≥98% (HPLC) | 25G | ₹9374.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 46404 | Mebendazole VETRANAL?, analytical standard | 250MG | ₹11669.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR2448 | Mebendazole Pharmaceutical Secondary Standard; Certified Reference Material | 300MG | ₹22764.98 | 2022-06-14 | Buy |
Properties
Melting point :288.5°C
Boiling point :436.98°C (rough estimate)
Density :1.1952 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Practically insoluble in water, in alcohol and in methylene chloride.
form :Solid
pka :pKa 3.43/9.93(H2O,t =25,I=0.025) (Uncertain)
color :White to Pale Beige
Water Solubility :35.4mg/L(25 ºC)
Merck :14,5768
BRN :759809
BCS Class :2,4
CAS DataBase Reference :31431-39-7(CAS DataBase Reference)
EPA Substance Registry System :Mebendazole (31431-39-7)
Boiling point :436.98°C (rough estimate)
Density :1.1952 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Practically insoluble in water, in alcohol and in methylene chloride.
form :Solid
pka :pKa 3.43/9.93(H2O,t =25,I=0.025) (Uncertain)
color :White to Pale Beige
Water Solubility :35.4mg/L(25 ºC)
Merck :14,5768
BRN :759809
BCS Class :2,4
CAS DataBase Reference :31431-39-7(CAS DataBase Reference)
EPA Substance Registry System :Mebendazole (31431-39-7)
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
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Description
Mebendazole is a broad-spectrum anthelmintic that is active against both larval and adult stages of nematodes selectively binding the β-subunit of tubulin, thereby inhibiting intestinal microtubule synthesis in the parasite (IC50 = 0.19 μM for Giardia in vitro). As a tubulin-binding agent, mebendazole also possesses antitumor properties, inducing apoptosis of various human carcinomas both in vitro and in vivo, thus preventing their growth and migration. Furthermore, mebendazole has been used to inhibit hedgehog signaling in cancer cells via suppression of the formation of the primary cilium, a microtubule-based organelle that functions as a signaling hub for hedgehog pathway activation. Additionally, mebendazole has been shown to stabilize the transcriptional activator HIF-1α and its downstream targets, abrogating oxidative neuronal death in primary neurons.More related product prices
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