MONOSIALOGANGLIOSIDE GM3
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- ₹44761.38 - ₹80267.38
- Product name: MONOSIALOGANGLIOSIDE GM3
- CAS: 54827-14-4
- MF: C64H118N2O21.H3N
- MW: 1268.66
- EINECS:
- MDL Number:MFCD00131139
- Synonyms:Monosialoganglioside GM3, Bovine (NH4+ salt);Monosialoganglioside GM3 (bovine)(aMMoniuM salt);Ganglioside M3;Hematoside;Sialosyllactosylceramide;(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-octadecanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid;Ganglioside GM3 (d18:1/18:0);(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-icosanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 0.5MG
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product numberG5642
- Product descriptionMonosialoganglioside GM3 from canine blood ≥98%, lyophilized powder
- Packaging0.5MG
- Price₹44761.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG5642
- Product descriptionMonosialoganglioside GM3 from canine blood ≥98%, lyophilized powder
- Packaging1MG
- Price₹80267.38
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G5642 | Monosialoganglioside GM3 from canine blood ≥98%, lyophilized powder | 0.5MG | ₹44761.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G5642 | Monosialoganglioside GM3 from canine blood ≥98%, lyophilized powder | 1MG | ₹80267.38 | 2022-06-14 | Buy |
Properties
storage temp. :−20°C
solubility :chloroform/methanol/water (9.5:9.5:1): 20mg/mLclear, colorless to light yellow
form :lyophilized powder
color :White
solubility :chloroform/methanol/water (9.5:9.5:1): 20mg/mLclear, colorless to light yellow
form :lyophilized powder
color :White
Safety Information
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| Signal word: | Warning | |||||||
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Description
Gangliosides are formed from a glycosphingolipid combined with one or more sialic acids at the oligosaccharide chain. They are anchored at the outer surface of the plasma membrane where they pack densely with cholesterol to form lipid microdomains that modulate both intra- and inter-cell signaling events. Gangliosides are often implicated in tumorigenesis since they can modulate cell surface events including proliferation, migration, and adhesion. Ganglioside GM3 is a simple monosialoganglioside that demonstrates both antiproliferative and proapoptic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. At 20 μM, it can suppress angiogenesis and reduce endothelial cell proliferation and migration by inhibiting VEGFR2 and Akt phosphorylation. Furthermore, ganglioside GM3 has been shown to induce the dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance.More related product prices
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