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MPP+ IODIDE

MPP+ IODIDE Structure
  • ₹18889.63 - ₹105673.65
  • Product name: MPP+ IODIDE
  • CAS: 36913-39-0
  • MF: C12H12IN
  • MW: 297.13485
  • EINECS:
  • MDL Number:MFCD00055096
  • Synonyms:N-Methyl-4-phenylpyridinium iodide;Pyridinium, 1-methyl-4-phenyl-, iodide;MPP+ iodide,1-Methyl-4-phenylpyridinium iodide;1-methyl-4-phenyl-pyridiniuiodide ;MPP+ IODIDE (ACTIVE METABOLITE OF DOPAMI NERGIC NEUROTOX;4-phenylpyridin-1-ium iodide;MPP+ IODIDE ISO 9001：2015 REACH;1-methyl-4-phenylpyridin-1-ium
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberD048
  • Product descriptionMPP+ iodide ≥98% (HPLC), powder
  • Packaging100MG
  • Price₹18889.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD048
  • Product descriptionMPP+ iodide ≥98% (HPLC), powder
  • Packaging1G
  • Price₹105673.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D048 MPP+ iodide ≥98% (HPLC), powder 100MG ₹18889.63 2022-06-14 Buy
Sigma-Aldrich(India) D048 MPP+ iodide ≥98% (HPLC), powder 1G ₹105673.65 2022-06-14 Buy

Properties

Melting point :166-168 °C
storage temp. :desiccated
solubility :0.1 M HCl: soluble
form :solid
color :yellow
InChIKey :RFDFRDXIIKROAI-UHFFFAOYSA-M

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

MPP+ iodide is a metabolite of dopaminergic neurotoxin MPTP which stimulates the production of the superoxide radical resulting in apoptosis in PC12 cells. Studies suggest that MPP+ iodide is a selective inhibitor of mitochondrial complex I and it decreases mitochondrial REDOX activity. In addition, GSK-3β is a mediator of MPP+ iodide induced neurotoxicity. Alternate studies indicate that the D-loop of human mtDNA is destabilized by MPP+ iodide via releasing the nascent H-strands of mtDNA.

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