NAPHTHOFLUORESCEIN
- ₹5239.2 - ₹21489.6
- Product name: NAPHTHOFLUORESCEIN
- CAS: 61419-02-1
- MF: C28H16O5
- MW: 432.42
- EINECS:634-716-5
- MDL Number:MFCD00329026
- Synonyms:NAPHTHOFLUORESCEIN;NAPHTHOFLUORESCEIN, FOR FLUORESCENCE;NAPHTHOFLUORESCEIN FOR FLUORESCENCE 95+%;Naphthafluorescein;Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one,3,11-dihydroxy-
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 100MG
- 500MG
- ManufacturerSigma-Aldrich(India)
- Product number70420
- Product descriptionNaphthofluorescein suitable for fluorescence
- Packaging100MG
- Price₹5239.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number70420
- Product descriptionNaphthofluorescein suitable for fluorescence
- Packaging500MG
- Price₹21489.6
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 70420 | Naphthofluorescein suitable for fluorescence | 100MG | ₹5239.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 70420 | Naphthofluorescein suitable for fluorescence | 500MG | ₹21489.6 | 2022-06-14 | Buy |
Properties
Melting point :189 °C (dec.)(lit.)
Boiling point :755.5±60.0 °C(Predicted)
Density :1.58±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble
form :A crystalline solid
pka :8.82±0.20(Predicted)
color :Purple to purplish red
BRN :61335
InChIKey :IXQIUDNVFVTQLJ-UHFFFAOYSA-N
EPA Substance Registry System :Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one, 3,11-dihydroxy- (61419-02-1)
Boiling point :755.5±60.0 °C(Predicted)
Density :1.58±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble
form :A crystalline solid
pka :8.82±0.20(Predicted)
color :Purple to purplish red
BRN :61335
InChIKey :IXQIUDNVFVTQLJ-UHFFFAOYSA-N
EPA Substance Registry System :Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one, 3,11-dihydroxy- (61419-02-1)
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway. Naphthofluorescein is a cell-permeable inhibitor of furin (IC50 = 12 μM). It inhibits furin-mediated cleavage of the pro-form of membrane type-1 matrix metalloproteinase MT1-MMP, resulting in decreased levels of active MT1-MMP. This, in turn, suppresses MMP-2 activation and reduces cell motility in CHO cells expressing proMT1-MMP. Napthofluorescein significantly inhibits the invasion of Matrigel by the human fibrosarcoma cell line, HT1080. The effects of this furin inhibitor on other furin-mediated processes, in vivo or in vitro, remain to be determined.Related product price
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