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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >Nicotinamide-N-oxide

Nicotinamide-N-oxide

Nicotinamide-N-oxide Structure
  • ₹3000
  • Product name: Nicotinamide-N-oxide
  • CAS: 1986-81-8
  • MF: C6H6N2O2
  • MW: 138.12
  • EINECS:217-859-4
  • MDL Number:MFCD00006202
  • Synonyms:1-OXY-NICOTINAMIDE;3-(AMINOCARBONYL)PYRIDINIUM-1-OLATE;AKOS 94294;NICOTINAMIDE 1-OXIDE;NICOTINAMIDE N-OXIDE;TIMTEC-BB SBB004187;3-Pyridinecarboxamide, 1-oxide;3-Pyridinecarboxamide,1-oxide(9CI)
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Brand

  • TCI Chemicals (India)

Package

  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberN0669
  • Product descriptionNicotinamide N-Oxide
  • Packaging5G
  • Price₹3000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) N0669 Nicotinamide N-Oxide 5G ₹3000 2022-05-26 Buy

Properties

Melting point :291-293 °C (dec.)(lit.)
Boiling point :253.51°C (rough estimate)
Density :1.3471 (rough estimate)
refractive index :1.5100 (estimate)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form :Solid
pka :14.38±0.50(Predicted)
color :White to Off-White
Sensitive :Hygroscopic
CAS DataBase Reference :1986-81-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Nicotinamide N-oxide is a metabolite of nicotinamide . It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; ), indicating cell differentiation, in HL-60 promyelocytic leukemia cells. Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity.

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