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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >Nifuroxazide

Nifuroxazide

Nifuroxazide Structure
  • ₹3972.78 - ₹7070
  • Product name: Nifuroxazide
  • CAS: 965-52-6
  • MF: C12H9N3O5
  • MW: 275.22
  • EINECS:213-522-0
  • MDL Number:MFCD00079482
  • Synonyms:(nitro-5’furfurylidene-2’)hydroxy-4benzhydrazide ;4-hydroxy-benzoicaci((5-nitro-2-furanyl)methylene)hydrazide ;NIFUROXAZIDE;p-hydroxybenzoic acid (5-nitrofurfurylidene) hydrazide;r.c.27-109 ;(5-Nitro-2-furfurylidene)(4-hydroxybenzoyl)hydrazine;4-Hydroxybenzoic Acid 2-[(5-Nitro-2-furanyl)methylene]hydrazide;Adral
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product number46494
  • Product descriptionNifuroxazide VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹3972.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number481984
  • Product descriptionNifuroxazide - CAS 965-52-6 - Calbiochem A cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcript
  • Packaging500MG
  • Price₹7070
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 46494 Nifuroxazide VETRANAL?, analytical standard 100MG ₹3972.78 2022-06-14 Buy
Sigma-Aldrich(India) 481984 Nifuroxazide - CAS 965-52-6 - Calbiochem A cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcript 500MG ₹7070 2022-06-14 Buy

Properties

Melting point :281-283°C
Boiling point :418.17°C (rough estimate)
Density :1.3877 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :Inert atmosphere,2-8°C
solubility :Practically insoluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
pka :8.36±0.15(Predicted)
form :Solid
color :Yellow
BRN :4264976
CAS DataBase Reference :965-52-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Nifuroxazide is a broad-spectrum nitrofuran antibiotic used against urinary tract infections and as therapy for acute diarrhea of bacterial origin. Like other nitrofuran antibiotics, nifuroxazide is activated during metabolism by microbial nitroreductases. It has been shown to block quorum sensing in P. aeruginosa. Nifuroxazide also inhibits the survival and migration of cancer cells, suppressing tumor growth and metastasis in vivo, at least in part by inhibiting STAT3 (IC50 = 10 μM).

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