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PPADS TETRASODIUM SALT

PPADS TETRASODIUM SALT Structure
  • ₹8140.4 - ₹104558.68
  • Product name: PPADS TETRASODIUM SALT
  • CAS: 192575-19-2
  • MF: C14H15N3NaO12PS2
  • MW: 535.37
  • EINECS:
  • MDL Number:MFCD00153865
  • Synonyms:PPADS Tetrasodium;PPADS tetrasodium salt, anhydrous;PPADS (sodium salt);PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULFONIC ACID TETRASODIUM SALT;PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID 4NA;PYRIDOXAL-PHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID TETRASODIUM;PPADS;pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 250MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberP178
  • Product descriptionPyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC)
  • Packaging10MG
  • Price₹8140.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP178
  • Product descriptionPyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC)
  • Packaging50MG
  • Price₹24897.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP178
  • Product descriptionPyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC)
  • Packaging250MG
  • Price₹104558.68
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P178 Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC) 10MG ₹8140.4 2022-06-14 Buy
Sigma-Aldrich(India) P178 Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC) 50MG ₹24897.5 2022-06-14 Buy
Sigma-Aldrich(India) P178 Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC) 250MG ₹104558.68 2022-06-14 Buy

Properties

storage temp. :−20°C
solubility :H2O: >10 mg/mL
form :solid
color :red to orange
Water Solubility :Soluble to 100 mM in water
Stability :Unstable in Aqueous Solution

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large variety of excitatory postsynaptic responses including fast transmission at central synapses, contraction of smooth muscle cells, platelet aggregation, macrophage activation, and apoptosis. PPADS is a non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50s = 1-2.6 μM), native P2Y2-like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors. PPADS antagonism of ATP-sensitive P2 receptors produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats.

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Suppliers and manufacturers

CLEARSYNTH LABS LTD.
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd Shanghai Yifei Biotechnology Co. , Ltd. Shanghai Maclean Biochemical Technology Co., LTD RD International Technology Co., Limited MedBioPharmaceutical Technology Inc Shanghai Hao Biological Technology Co., Ltd. ShangHai Caerulum Pharma Discovery Co., Ltd. Changzhou Bojia Biomedical Technology Co., Ltd.