PUROMYCIN AMINONUCLEOSIDE
- ₹15999.35 - ₹218946.45
- Product name: PUROMYCIN AMINONUCLEOSIDE
- CAS: 58-60-6
- MF: C12H18N6O3
- MW: 294.31
- EINECS:200-388-3
- MDL Number:MFCD00063462
- Synonyms:3’-amino-3’-deoxy-n,n-dimethyl-adenosin ;6-(dimethylamino)-9-(3-amino-3-deoxy-beta-d-ribofuranosyl)purine ;9-(3-amino-3-deoxy-beta-d-ribofuranosyl)-6-(dimethylamino)-9h-purine ;aminonucleoside ;aminonucleosidepuromycin ;stylomycinaminonucleoside ;PUROMYCIN AMINONUCLEOSIDE;6-DIMETHYLAMIN-9-[3'-AMINO-3'DEOXYRIBOSYL]-PURINE
4 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 100MG
- 500MG
- 1G
- 1ML
- ManufacturerSigma-Aldrich(India)
- Product numberSBR00017
- Product descriptionPuromycin aminonucleoside Ready Made Solution 10?mg/mL in water
- Packaging1ML
- Price₹15999.35
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP7130
- Product descriptionPuromycin aminonucleoside
- Packaging100MG
- Price₹30602.28
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP7130
- Product descriptionPuromycin aminonucleoside
- Packaging500MG
- Price₹116563.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP7130
- Product descriptionPuromycin aminonucleoside
- Packaging1G
- Price₹218946.45
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SBR00017 | Puromycin aminonucleoside Ready Made Solution 10?mg/mL in water | 1ML | ₹15999.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P7130 | Puromycin aminonucleoside | 100MG | ₹30602.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P7130 | Puromycin aminonucleoside | 500MG | ₹116563.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P7130 | Puromycin aminonucleoside | 1G | ₹218946.45 | 2022-06-14 | Buy |
Properties
Melting point :235℃ (Decomposition)
Boiling point :436.08°C (rough estimate)
Density :1.2131 (rough estimate)
refractive index :1.7000 (estimate)
Flash point :>110°(230°F)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O: 50 mg/mL, clear, slightly yellow
form :liquid
pka :13.26±0.70(Predicted)
color :White
Water Solubility :Soluble in water at 50mg/ml. May require heating
BRN :93902
Stability :Stable for 1 year as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
InChIKey :RYSMHWILUNYBFW-GRIPGOBMSA-N
EPA Substance Registry System :Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl- (58-60-6)
Boiling point :436.08°C (rough estimate)
Density :1.2131 (rough estimate)
refractive index :1.7000 (estimate)
Flash point :>110°(230°F)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O: 50 mg/mL, clear, slightly yellow
form :liquid
pka :13.26±0.70(Predicted)
color :White
Water Solubility :Soluble in water at 50mg/ml. May require heating
BRN :93902
Stability :Stable for 1 year as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
InChIKey :RYSMHWILUNYBFW-GRIPGOBMSA-N
EPA Substance Registry System :Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl- (58-60-6)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Puromycin is an aminonucleoside antibiotic that blocks protein synthesis in both prokaryotes and eukaryotes by causing premature termination of nascent polypeptide chains. Puromycin aminonucleoside (PANS) is the aminonucleoside portion of puromycin. This analog cannot inhibit protein synthesis or induce apoptosis. Instead it is used to induce nephropathy in laboratory animal models to study focal and segmental glomerulosclerosis, the induction of nephrosis, and the events leading to proteinuria. When administered to rats at 0.5-5 μM, PANS affects glomerular epithelial cell adhesion, reducing α3β1 integrin expression. PANS also has been shown to decrease nephrin and podocin expression.Related product price
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