Pyranoridine phosphate
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- ₹22310.33
- Product name: Pyranoridine phosphate
- CAS: 76748-86-2
- MF: C29H35ClN5O6P
- MW: 616.05
- EINECS:
- MDL Number:MFCD05863545
- Synonyms:PYRANORIDINE TETRAPHOSPHATE;4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pheno ;phosphate(1:4) ;pyranoridinephosphate ;Pyranaridine tetraphosphate;4-[(7-Chloro-2-methoxy-1,5-dihydropyrido[3,2-b]quinolin-10-yl)imino]-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one phosphate (1:4);2-Methoxy-7-chloro-10[3′,5′-bis(pyrrolidinyl-1-methyl-)4′-hydroxyphenyl]aminobenzyl-(b)-1,5-naphthyridine tetraphosphate;4-[(7-chloro-2-methoxy-1,5-dihydrobenzo[b][1,5]naphthyridin-10-yl)imino]-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one,phosphoricaci
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 250MG
- ManufacturerSigma-Aldrich(India)
- Product numberP0049
- Product descriptionPyronaridine tetraphosphate
- Packaging250MG
- Price₹22310.33
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P0049 | Pyronaridine tetraphosphate | 250MG | ₹22310.33 | 2022-06-14 | Buy |
Properties
Melting point :233-236° (dec)
storage temp. :2-8°C
solubility :acetic acid: soluble5mg/mL
form :solid
color :Light yellow to yellow
InChIKey :YKUQEKXHQFYULM-UHFFFAOYSA-N
storage temp. :2-8°C
solubility :acetic acid: soluble5mg/mL
form :solid
color :Light yellow to yellow
InChIKey :YKUQEKXHQFYULM-UHFFFAOYSA-N
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Pyronaridine (PND) is a potent antimalarial compound developed in China over 40 years ago. It inhibits the growth of P. falciparum during the asexual stage and early gametocyte stages (I and II) with an IC50 value of approximately 10 nM. PND is highly effective against artemisinin-resistant malaria and can be used in combination therapy, particularly with the artemisinin derivative, artesunate . PND, alone or in combination with artesunate, prevents recrudescence of parasites. Resistance to pyronaridine may be linked to genetic variations in the P. falciparum multidrug resistance protein 1.Related product price
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